Webinars – Life science
Label free chemical imaging of fresh, hydrated living tissues and embryos with submicron IR (O-PTIR)
Dr. Oxana Klementieva
Lund University, Sweden
Department of experimental
Medical science.
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Please join Prof Oxana Klementieva, Lund University, in this two-part webinar based on her recent publication to learn how, for the first time, typical IR spectra and chemical IR images, at submicron resolution were acquired without water interferences in the protein bands, on freshly prepared and hydrated biopsies, tissue slices, and living organisms without compromising sample viability and function.
This webinar will cover;
- The analysis of fresh mouse brain sections on glass slides, imaging beta-sheet rich amyloid structures
- Time resolved imaging of living tissues showing evolution of beta-sheets and lipid oxidation
- How living lung tissue exposed to different levels of IR energy demonstrate no functional impairment
- Living salamander embryos imaged for lipid droplets, with no impact of measurement on embryo development
Additionally, Dr Mustafa Kansiz, Director of Product Management at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman with co-located fluorescence widefield imaging, with advances now delivering sub-500nm IR spatial resolution.
These breakthroughs will be presented in this two-part event, together with a range of application examples, from life sciences, covering live cell lipid metabolism, single cell bacterial measurements with stable isotope labelling to fixed tissues for cell typing.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Label free chemical imaging of fresh, hydrated living tissues and embryos with submicron IR (O-PTIR)
Dr. Oxana Klementieva
Lund University, Sweden
Department of experimental
Medical science.
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Please join Prof Oxana Klementieva, Lund University, in this two-part webinar based on her recent publication to learn how, for the first time, typical IR spectra and chemical IR images, at submicron resolution were acquired without water interferences in the protein bands, on freshly prepared and hydrated biopsies, tissue slices, and living organisms without compromising sample viability and function.
This webinar will cover;
- The analysis of fresh mouse brain sections on glass slides, imaging beta-sheet rich amyloid structures
- Time resolved imaging of living tissues showing evolution of beta-sheets and lipid oxidation
- How living lung tissue exposed to different levels of IR energy demonstrate no functional impairment
- Living salamander embryos imaged for lipid droplets, with no impact of measurement on embryo development
Additionally, Dr Mustafa Kansiz, Director of Product Management at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman with co-located fluorescence widefield imaging, with advances now delivering sub-500nm IR spatial resolution.
These breakthroughs will be presented in this two-part event, together with a range of application examples, from life sciences, covering live cell lipid metabolism, single cell bacterial measurements with stable isotope labelling to fixed tissues for cell typing.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Sub-micron IR imaging of lipid metabolism in single cells with IR tags
Dr Yeran Bai
Department of Molecular,
Cellular and Developmental Biology
University of California, Santa Barbara
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Dr Bai will present a single cell metabolic imaging platform to enable direct imaging of lipid metabolism, detecting newly synthesized lipids, with high specificity in various human-derived 2D and 3D culture systems. Furthermore, the platform provides for simultaneous fluorescence imaging for cell-type identification. Additionally, Dr Mustafa Kansiz, Director of Product Management at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman with co-located fluorescence widefield imaging, with advances now delivering sub-500nm IR spatial resolution.
This two-part event will present these breakthroughs with a range of application examples, from life sciences to particulates/microplastics, failure analysis, materials sciences, and more.
Sub-micron IR imaging of lipid metabolism in single cells with IR tags
Dr Yeran Bai
Department of Molecular,
Cellular and Developmental Biology
University of California, Santa Barbara
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Dr Bai will present a single cell metabolic imaging platform to enable direct imaging of lipid metabolism, detecting newly synthesized lipids, with high specificity in various human-derived 2D and 3D culture systems. Furthermore, the platform provides for simultaneous fluorescence imaging for cell-type identification. Additionally, Dr Mustafa Kansiz, Director of Product Management at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman with co-located fluorescence widefield imaging, with advances now delivering sub-500nm IR spatial resolution.
This two-part event will present these breakthroughs with a range of application examples, from life sciences to particulates/microplastics, failure analysis, materials sciences, and more.
Live cell imaging by sub-micron IR microscopy
Tracking de novo lipogenesis in single cells with stable isotope probes
Asst. Prof Caitlin Davis
Department of Chemistry, Yale University
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Results from her recent breakthrough publication – Spatiotemporal Heterogeneity of De Novo Lipogenesis in Fixed and Living Single Cells will be presented. The research is centered on DNL, which can become dysregulated in such diseases like cancer, obesity, type II diabetes and nonalcoholic fatty liver disease
O-PTIR enabled a deeper understanding of DNL because conventional FTIR/QCL microscopy tools lack the spatial resolution and ability to work with cells in water.
Learn how O-PTIR has been uniquely utilized to track DNL, in space (with submicron resolution) and time, as isotopically labelled glucose is converted to lipids in live metabolically active cells in water (non-deuterated).
O-PTIR achieves the same high spatial resolution of Raman microscopy, but with the rich information content of IR spectroscopy (eg protein secondary structure) with high sensitivity in seconds
O-PTIR eliminates many traditional challenges of Raman microscopy, such poor sensitivity of cells and fluorescence interferences.
O-PTIR enables exploration of the synergistic complementarity between IR and Raman while allowing the user to collect submicron IR and Raman spectra simultaneously, from the same spot, at the same time with the same spatial resolution. These breakthrough advances will be presented together with a range of biomedical application examples, from single bacteria, tissues and cells in this two-part event.
Part 1: Introduction to multi-modal submicron O-PTIR/Raman/Fluorescence
- Challenges of current direct IR (FTIR & QCL) and Raman micro-spectroscopic techniques applied to the analysis of biological samples and how O-PTIR overcome all of these challenges
- Demonstration of sub-500nm IR spatial resolution
- Co-located sub-micron IR and fluorescence epi-widefield imaging
- Examples across a wide range of biological samples, such as cells, tissues and bacteria
Part 2: Asst Prof Davis – Live cell imaging by sub-micron IR: Tracking de novo lipogenesis in single cells with stable isotope probes
- Overview of de novo lipogenesis (DNL) and it’s role in many modern diseases such as cancer, obesity, diabetes and nonalcoholic fatty liver disease
- Challenges of lipid imaging using traditional techniques
- Use of sub-micron IR (O-PTIR) for the spatiotemporal tracking of DNL using stable isotope labelled glucose in live cells in regular water
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Live cell imaging by sub-micron IR microscopy
Tracking de novo lipogenesis in single cells with stable isotope probes
Asst. Prof Caitlin Davis
Department of Chemistry, Yale University
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Results from her recent breakthrough publication – Spatiotemporal Heterogeneity of De Novo Lipogenesis in Fixed and Living Single Cells will be presented. The research is centered on DNL, which can become dysregulated in such diseases like cancer, obesity, type II diabetes and nonalcoholic fatty liver disease
O-PTIR enabled a deeper understanding of DNL because conventional FTIR/QCL microscopy tools lack the spatial resolution and ability to work with cells in water.
Learn how O-PTIR has been uniquely utilized to track DNL, in space (with submicron resolution) and time, as isotopically labelled glucose is converted to lipids in live metabolically active cells in water (non-deuterated).
O-PTIR achieves the same high spatial resolution of Raman microscopy, but with the rich information content of IR spectroscopy (eg protein secondary structure) with high sensitivity in seconds
O-PTIR eliminates many traditional challenges of Raman microscopy, such poor sensitivity of cells and fluorescence interferences.
O-PTIR enables exploration of the synergistic complementarity between IR and Raman while allowing the user to collect submicron IR and Raman spectra simultaneously, from the same spot, at the same time with the same spatial resolution. These breakthrough advances will be presented together with a range of biomedical application examples, from single bacteria, tissues and cells in this two-part event.
Part 1: Introduction to multi-modal submicron O-PTIR/Raman/Fluorescence
- Challenges of current direct IR (FTIR & QCL) and Raman micro-spectroscopic techniques applied to the analysis of biological samples and how O-PTIR overcome all of these challenges
- Demonstration of sub-500nm IR spatial resolution
- Co-located sub-micron IR and fluorescence epi-widefield imaging
- Examples across a wide range of biological samples, such as cells, tissues and bacteria
Part 2: Asst Prof Davis – Live cell imaging by sub-micron IR: Tracking de novo lipogenesis in single cells with stable isotope probes
- Overview of de novo lipogenesis (DNL) and it’s role in many modern diseases such as cancer, obesity, diabetes and nonalcoholic fatty liver disease
- Challenges of lipid imaging using traditional techniques
- Use of sub-micron IR (O-PTIR) for the spatiotemporal tracking of DNL using stable isotope labelled glucose in live cells in regular water
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Overcoming the challenges of Raman microscopy with O-PTIR spectroscopy:
Life science applications from single cell bacteria, live cells and tissues
Presenters:
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Prof. Roy Goodacre
Department of Biochemistry and Systems Biology
University of Liverpool
Please join Prof Roy Goodacre, Liverpool University in this two-part webinar to learn about how his research group is applying submicron IR (O-PTIR) with simultaneous Raman to the study of microbial communities, at the single cell level to explore inter-cell biochemical, metabolomic and anti-microbial resistance differences utilising stable isotope labelling techniques.
Learn, how many of the traditional challenges of Raman microscopy, such poor sensitivity of individual bacterial cells and fluorescence interferences are eliminated with the use of the breakthrough technique – Optical Photothermal Infrared (O-PTIR) spectroscopy, delivering the same high spatial resolution of Raman microscopy, but with the rich information content of IR spectroscopy (eg proteins) with high sensitivity in seconds, without any autofluorescence interferences. Additionally, the well-known vibrational spectroscopic complementarity between IR and Raman can also be fully exploited with full synergy through the ability to now collect submicron IR and Raman spectra simultaneously, from the same spot, at the same time with the same spatial resolution.
Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview, comparisons to traditional IR and Raman spectroscopy, covering submicron simultaneous IR+Raman together with a range of life science application examples (cells, tissues and live cells) in this two part event.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Overcoming the challenges of Raman microscopy with O-PTIR spectroscopy:
Life science applications from single cell bacteria, live cells and tissues
Presenters:
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Prof. Roy Goodacre
Department of Biochemistry and Systems Biology
University of Liverpool
Learn, how many of the traditional challenges of Raman microscopy, such poor sensitivity of individual bacterial cells and fluorescence interferences are eliminated with the use of the breakthrough technique – Optical Photothermal Infrared (O-PTIR) spectroscopy, delivering the same high spatial resolution of Raman microscopy, but with the rich information content of IR spectroscopy (eg proteins) with high sensitivity in seconds, without any autofluorescence interferences. Additionally, the well-known vibrational spectroscopic complementarity between IR and Raman can also be fully exploited with full synergy through the ability to now collect submicron IR and Raman spectra simultaneously, from the same spot, at the same time with the same spatial resolution.
Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview, comparisons to traditional IR and Raman spectroscopy, covering submicron simultaneous IR+Raman together with a range of life science application examples (cells, tissues and live cells) in this two part event.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Single bacterial cell characterization with submicron IR and simultaneous Raman spectroscopy – A world first
Dr Cassio Lima
Post Doc, Research Associate
Deptartment of Biochemistry and System Biology
University of Liverpool, UK
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Dr Cassio Lima, will present results from his recent paper entitled, “Simultaneous Raman and infrared spectroscopy – a novel combination for studying bacterial infections at the single cell level”, published this month in Chemical Science. Results show how that for the first time and applied to twelve bacterial clinical isolates, the complementarity of IR and Raman can truly be exploited for single cell bacterial analyses and how O-PTIR generates more reproducible spectra with tighter clustering compared to Raman.
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman together with a range of biomedical application examples in this two part event.
A summary of the webinar includes;
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) and Simultaneous Raman applied to;
– Sepsis relevant bacterial cell analysis (twelve clinical isolates)
– Single bacterial cells characterization (with simultaneous IR and Raman)
– Exploiting the complementarity of IR (stronger protein signals) and Raman (strong pigment signals)
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Single bacterial cell characterization with submicron IR and simultaneous Raman spectroscopy – A world first
Dr Cassio Lima
Post Doc, Research Associate
Deptartment of Biochemistry and System Biology
University of Liverpool, UK
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Dr Cassio Lima, will present results from his recent paper entitled, “Simultaneous Raman and infrared spectroscopy – a novel combination for studying bacterial infections at the single cell level”, published this month in Chemical Science. Results show how that for the first time and applied to 12 bacterial clinical isolates, the complementarity of IR and Raman can truly be exploited for single cell bacterial analyses and how O-PTIR generates more reproducible spectra with tighter clustering compared to Raman.
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman together with a range of biomedical application examples in this two part event.
A summary of the webinar includes;
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) and Simultaneous Raman applied to;
– Sepsis relevant bacterial cell analysis (12 clinical isolates)
– Single bacterial cells characterization (with simultaneous IR and Raman)
– Exploiting the complementarity of IR (stronger protein signals) and Raman (strong pigment signals)
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Workshop from SPEC2022
Submicron IR and simultaneous Raman
O-PTIR technology overview with biomedical applications
We assembled a lineup of top researches in biospectroscopy to hear from them how they’re using the breakthrough novel O-PTIR technology, with its submicron IR and simultaneous Raman capabilities.
Dr Mustafa Kansiz
Photothermal Spectroscopy Corp
An exploration of OPTIR and concomitant Raman for single cell analysis
Prof Peter Gardner
Manchester Institute of Biotechnology, The University of Manchester
Simultaneous Raman and submicron infrared spectroscopy: A novel combination for studying bacterial samples at the single cell level
Dr. Cassio Lima
Department of Biochemistry and Systems Biology, Institute of Systems, Molecular, and Integrative Biology, University of Liverpool
Optical photothermal infrared spectroscopic applications for microplastic, cell and tissue studies: Comparison with FTIR and Raman spectroscopy
Dr. Christoph Krafft
Leibniz Institute of Photonic Technology, Jena, Germany
Advances in bone tissue and bone-biomaterial interface characterization
Prof Havard J. Haugen
Biomaterials group at The Institute of Clinical Dentistry
Faculty of Dentistry, University of Oslo, Norway
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
See his recent publication here.
Additionally, Dr Mustafa Kansiz, Photothermal Spectroscopy Corp, will provide a brief technique, including submicron simultaneous IR+Raman overview together a range of application examples in this two part event.
A summary of the webinar includes;
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) applied to;
-Bone tissue and bone-biomaterial interfaces
-FLARE (Fluorescence Imaging) combination with O-PTIR
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Advances in bone tissue and bone-biomaterial interface characterization
Prof Havard J. Haugen
Biomaterials group at The Institute of Clinical Dentistry
Faculty of Dentistry, University of Oslo, Norway
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
See his recent publication here.
Additionally, Dr Mustafa Kansiz, Photothermal Spectroscopy Corp, will provide a brief technique, including submicron simultaneous IR+Raman overview together a range of application examples in this two part event.
A summary of the webinar includes;
-
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) applied to;
-Bone Tissue & Bone-Biomaterial interfaces
-FLARE (Fluorescence Imaging) combination with O-PTIR
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Live cells, tissues and single cell bacterial analysis using submicron IR and simultaneous Raman spectroscopy
Available for viewing
Leibniz Institute of Photonic Technology, Jena, Germany
Director of Product Management and Marketing, Photothermal Spectroscopy Corp
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview together a range of application examples in this two part event.
A summary of the webinar includes;
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) and simultaneous Raman applied to life science samples such as:
– Live cells in water
– Tissues
– Single cell bacteria
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Live cells, tissues and single cell bacterial analysis using submicron IR and simultaneous Raman spectroscopy
Available for viewing
Presenters:
Dr. Christoph Krafft
Leibniz Institute of Photonic Technology, Jena, Germany
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview together a range of application examples in this two part event.
A summary of the webinar includes;
- Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Submicron IR (O-PTIR) and simultaneous Raman applied to life science samples such as:
– Live cells in water
– Tissues
– Single cell bacteria
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Correlative submicron IR and X-Ray fluorescence for molecular and elemental imaging of neurons
Available for viewing
Associate Professor
Lund University, Sweden
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
A summary of the webinar includes;
- Introduction to submicron IR with the breakthrough technique of O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Combination of sub-micron IR nd Synchrotron X-Ray Fluorescence for molecular and elemental imaging of neurons directly
- Results show that in primary AD-like neurons, iron cluster co-localise with amyloid-beta sheet protein structures and oxidised lipids
In conjunction with Dr Mustafa Kansiz, who will present an initial overview of the technique with further life science (live cells, tissues and bacteria) application examples and Prof Oxana Klementieva who will detail her recent research publication on this topic, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Correlative submicron IR and X-Ray fluorescence for molecular and elemental imaging of neurons
Available for viewing
Presenters:
Prof. Oxana Klementieva
Associate Professor
Lund University, Sweden
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp
A summary of the webinar includes;
- Introduction to submicron IR with the breakthrough technique of O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
- Combination of sub-micron IR nd Synchrotron X-Ray Fluorescence for molecular and elemental imaging of neurons directly
- Results show that in primary AD-like neurons, iron cluster co-localise with amyloid-beta sheet protein structures and oxidised lipids
In conjunction with Dr Mustafa Kansiz, who will present an initial overview of the technique with further life science (live cells, tissues and bacteria) application examples and Prof Oxana Klementieva who will detail her recent research publication on this topic, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Sub-cellular resolution simultaneous IR+Raman (O-PTIR) imaging for biomedical applications
Available for viewing
Assistant Professor, Department of Electronic and Computer Engineering
University of Houston
Director of Product Management
and Marketing
Photothermal Spectroscopy Corp
O-PTIR imaging for spectral-histopathology of ovarian tissues
Demonstration of 20x improvement of spatial resolution vs FTIR for tissues
Bone disorders and collagen deposition studied with O-PTIR
Other examples of IR+Raman, live cell imaging, single cell bacteria, microplastics etc
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique, including simultaneous sub-micron IR+Raman microscopy with further life science research examples (live cell imaging, single cell bacteria etc) we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Sub-cellular resolution simultaneous IR+Raman (O-PTIR) imaging for biomedical applications
Available for viewing
Presenters:
Dr. Rohith Reddy
Assistant Professor, Deptartment of Electronic and Computer Engineering, University of Houston
Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp
O-PTIR imaging for spectral-histopathology of ovarian tissues
Demonstration of 20x improvement of spatial resolution vs FTIR for tissues
Bone disorders and collagen deposition studied with O-PTIR
Other examples of IR+Raman, live cell imaging, single cell bacteria, microplastics etc
Asst Prof Rohith Reddy, will discuss how the combination of biochemically relevant molecular information along with morphology makes Mid-Infrared Spectroscopic Imaging (MIRSI) especially useful in medical applications such as cancer research. Early diagnosis of cancers, like ovarian cancer, is essential for improving survival. To automate the process of disease diagnosis, we perform MIRSI imaging followed by machine learning. However, this requires data of high signal-to-noise ratio and resolution. In this presentation, we use O-PTIR with an order of magnitude higher resolution relative to FT-IR imaging and present histopathology results for ovarian tissue. Additionally, bone disorders such as osteosclerosis and collagen deposition have spectroscopic signatures that can also e identified using MIRSI. We present high-resolution O-PTIR imaging data and results from studies of challenging clinical bone samples.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique, including simultaneous sub-micron IR+Raman microscopy with further life science research examples (live cell imaging, single cell bacteria etc) we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Live single cell analysis with simultaneous submicron IR+Raman spectroscopy:
Available for viewing
Life science applications of O-PTIR, from tissues, single bacteria to live cells
Prof. Peter Gardner
Chemical Engineering and Analytical Science, Manchester University, UK
Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp
Using this experimental configuration, all biologically relevant IR vibrations are probed, with further vibration complementarity provided by the concomitant Raman data, generating a full vibrational spectroscopic profile. Pancreatic and breast cancer cell lines are used as model cells to demonstrate these exciting new capabilities.
These combined modalities are shown to be able to analyze subcellular structures in both fixed and, more importantly, live cells under aqueous conditions. We show that the protein secondary structure and lipid-rich bodies can be identified on the submicron scale.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique with further life science research examples (tissues, single cell bacteria etc) we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Live single cell analysis with simultaneous submicron IR+Raman spectroscopy:
Available for viewing
Life science applications of O-PTIR, from tissues, single bacteria to live cells
Presenters:
Prof. Peter Gardner
Chemical Engineering and Analytical Science, Manchester University, UK
Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp
Using this experimental configuration, all biologically relevant IR vibrations are probed, with further vibration complementarity provided by the concomitant Raman data, generating a full vibrational spectroscopic profile. Pancreatic and breast cancer cell lines are used as model cells to demonstrate these exciting new capabilities.
These combined modalities are shown to be able to analyze subcellular structures in both fixed and, more importantly, live cells under aqueous conditions. We show that the protein secondary structure and lipid-rich bodies can be identified on the submicron scale.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique with further life science research examples (tissues, single cell bacteria etc) we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Single and intra-cell bacterial IR spectroscopy:
Life science applications of O-PTIR, from tissues to live cells and single cell bacteria
Available for viewing
Prof. Roy Goodacre
Department of Biochemistry and Systems Biology
University of Liverpool
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Prof Roy Goodacre (Uni Liverpool, UK) will present results from his recent publication on stable isotope labelled bacteria, studied with single cell O-PTIR to reveal insights into bacterial metabolism, not only as communities, but also interactions between microorganisms. This presents a significant advance as most studies have focused on evaluating communities of cells, due to the poor spatial resolution achieved by classical infrared microspectrometers and, to date, there is no study evaluating the incorporation of labelled compounds by bacteria at single cell levels using infrared spectroscopy.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Single and intra-cell bacterial IR spectroscopy:
Life science applications of O-PTIR, from tissues to live cells and single cell bacteria
Available for viewing
Prof. Roy Goodacre
Department of Biochemistry and Systems Biology
University of Liverpool
Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp
Prof Roy Goodacre (Uni Liverpool, UK) will present results from his recent publication on stable isotope labelled bacteria, studied with single cell O-PTIR to reveal insights into bacterial metabolism, not only as communities, but also interactions between microorganisms. This presents a significant advance as most studies have focused on evaluating communities of cells, due to the poor spatial resolution achieved by classical infrared microspectrometers and, to date, there is no study evaluating the incorporation of labelled compounds by bacteria at single cell levels using infrared spectroscopy.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Collagen orientation, fiber to submicron fibril life science applications of O-PTIR, from tissues to single cells and bacteria
Available for viewing
Prof. Kathy Gough
Dept of Chemistry, University of Manitoba, Canada
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Collagen orientation, fiber to submicron fibril life science applications of O-PTIR, from tissues to single cells and bacteria
Available for viewing
Prof. Kathy Gough
Dept of Chemistry, University of Manitoba, Canida
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Amyloid aggregates in neurons – Life science applications using submicron simultaneous IR and Raman microscopy
Available for viewing
(Publication chosen for cover of Advanced Science, Mar 18, 2020)
Dr. Oxana Klementieva
Associate Professor
Lund University, Sweden
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Amyloid aggregates in neurons – Life science applications using submicron simultaneous IR and Raman microscopy
(Publication chosen for cover of Advanced Science, Mar 18, 2020)
Available for viewing
Presenters:
Dr. Oxana Klementieva
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Life science applications using novel submicron simultaneous IR and Raman microscopy – A new paradigm in vibrational spectroscopy
Available for viewing
Prof. Ji-Xin Cheng
Moustakas Professor in Photonics and Optoelectronics, Professor of ECE, BME, Chemistry & Physics, Boston University Photonics Center
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp
This webinar will cover the invention, various strategies of instrumentation, broad applications and commercialization of far-field Optical Photothermal IR (O-PTIR) microscopy, presenting both scanning-based and wide-field approaches with various life science applications. Integration with Raman spectroscopy will also be highlighted.
Learn how now, for the first-time live cells can be measured in water, with submicron spatial resolution, with IR spectral information, allowing for cellular metabolism and drug uptake studies for example.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Life science applications using novel submicron simultaneous IR and Raman microscopy – A new paradigm in vibrational spectroscopy
Available for viewing
Prof. Ji-Xin Cheng
Moustakas Professor in Photonics and Optoelectronics, Professor of ECE, BME, Chemistry & Physics, Boston University Photonics Center
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp
This webinar will cover the invention, various strategies of instrumentation, broad applications and commercialization of far-field Optical Photothermal IR (O-PTIR) microscopy, presenting both scanning-based and wide-field approaches with various life science applications. Integration with Raman spectroscopy will also be highlighted.
Learn how now, for the first-time live cells can be measured in water, with submicron spatial resolution, with IR spectral information, allowing for cellular metabolism and drug uptake studies for example.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.
Photothermal Spectroscopy Corp.
325 Chapala Street
Santa Barbara, CA 93101
Phone: (805) 845-6568
Email: info [at] photothermal.com