Slide

New: Sub-500nm IR with simultaneous Raman
and co-located Fluorescence microscopy

Beyond limits anim

O-PTIR: Beyond the limits of traditional IR microscopy

O-PTIR: Beyond the limits of traditional IR microscopy

O-PTIR: Beyond the
limits of traditional
IR microscopy

Non-contact measurement

Non-contact measurement

Non-contact measurement

Submicron
spatial resolution

Submicron
spatial resolution

Submicron
spatial resolution

All the benefits of ATR
without its contact
related limitations

All the benefits of ATR
without its contact
related limitations

All the benefits of ATR
without its contact
related limitations

mIRage vs traditional techniques
IRandRaman
IR+Raman/IR plus Raman

Same spot.

Same resolution.

Same time.

Registered conference attendees will be sent a workshop registration link: CONFERENCE REGISTRATION ►
Register for the virtual online access to workshop here: VIRTUAL REGISTRATION ►
Virtual time, June 19, Sunday 2:30-4:30 IST (Irish Standard Time) GMT+1

Submicron simultaneous IR+Raman microscope combines optical photothermal infrared spectroscopy (O-PTIR) with Raman.

FTIR and Raman spectroscopy for material and life science analysis are well established technologies, but have practical and theoretical limitations. Now, with PSC’s new breakthrough technique using O-PTIR and Raman on the mIRage photothermal spectroscopy infrared microscope, those limitations have been shattered.

A new patented technique, photothermal spectroscopy based O-PTIR overcomes the poor resolution of traditional FTIR microscopy with the novel use of a dual purpose visible light probe which is not only capable of enabling submicron IR spatial resolution, but also doubles as a Raman excitation laser providing submicron simultaneous IR+Raman spectroscopy on a single platform.

This combination generates complementary and confirmatory analysis through IR and Raman spectroscopy for a more detailed and thorough characterization and the ultimate in vibrational spectroscopic synergy.

By working in reflection mode this technique eliminates complex sample preparation and generates high quality spectra without any dispersive scatter artifacts comparable to FTIR transmission/ATR spectra. Additionally, O-PTIR is not affected at all by fluorescence interference, a key limitation of Raman spectroscopy, thus allowing for sub-micron molecular characterization that is completely fluorescence free.

Now with the mIRage-LS, the addition of co-located Fluorescence microscopy provides a new, innovative platform for advanced life science characterization with a chemical spatial resolution of <500nm. The mIRage-LS provides fluorescence guided IR spectroscopy to easily target bio-molecular structures of interest and resolve their chemical molecular structure.

Illustration showing the cycle of steam sterilization of baby bottle nipples creating a film of microplastics.=
Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy

We successfully used O-PTIR microspectroscopy to identify small microplastics down to 600 nm to demonstrate the formation of cyclic and branched polysiloxane- or polyimide-containing micro(nano)plastics during the steam disinfection of silicone teats (baby bottle nipples]. https://doi.org/10.1038/s41565-021-00998-x

Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy
Illustration showing the cycle of steam sterilization of baby bottle nipples creating a film of microplastics.=

We successfully used O-PTIR microspectroscopy to identify small microplastics down to 600 nm to demonstrate the formation of cyclic and branched polysiloxane- or polyimide-containing micro(nano)plastics during the steam disinfection of silicone teats (baby bottle nipples]. https://doi.org/10.1038/s41565-021-00998-x

mIRage product image

mIRage IR Microscope

Changing the field of IR spectroscopy

Optical photothermal infrared spectroscopy overcomes the key limitations of FTIR and Raman infrared spectroscopy by providing sub-micron, non-contact and fluorescence free rapid analysis. When combined with simultaneous Raman the results are a unique complementary and confirmatory sample analysis experience.

O-PTIR: Optical
photothermal spectroscopy

Achieve submicron IR spatial resolution
in non-contact reflection mode

IR+Raman/IR plus RamanSame spot.
Same resolution.
Same time.

Wide applications capabilities

O-PTIR enables unique breakthrough applications in the fields of failure analysis, pharmaceuticals, life science, identification of organic particles, and more.

Illustration showing IR+Raman analysis of computer hard drive contamination

New “dual range (C-H/FP)” QCL

A new “dual range (C-H/FP)” QCL option is available that now covers, in a single unit, the C-H stretch and fingerprint ranges (3000-2700, 1800-950cm-1)

Library (Wiley KnowItAll) search results delivered >95% match
O-PTIR spectra collected in reflection mode. Displayed spectra are raw and unprocessed (<5sec collection time, ~500nm spot size)
O-PTIR spectra are measured off thick polymers (mm’s), vs library FTIR references data off thin films (~10microns)

Spectra showing new “Dual Range (C-H/FP)” QCL

Stay updated.

Photothermal Spectroscopy Corp

325 Chapala Street
Santa Barbara, CA 93101

Phone: (805) 845-6568
Email: info [at] photothermal.com