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Beyond limits anim

O-PTIR: Beyond the limits of traditional IR microscopy

O-PTIR: Beyond the limits of traditional IR microscopy

O-PTIR: Beyond the
limits of traditional
IR microscopy

Non-contact measurement

Non-contact measurement

Non-contact measurement

Submicron
spatial resolution

Submicron
spatial resolution

Submicron
spatial resolution

All the benefits of ATR
without its contact
related limitations

All the benefits of ATR
without its contact
related limitations

All the benefits of ATR
without its contact
related limitations

mIRage vs traditional techniques
IRandRaman
IR+Raman/IR plus Raman

Same spot.

Same resolution.

Same time.

Banner for the Advances in bone tissue and bone-biomaterial interface and characterization webinar

Presenters

Dr. Oxana Klementieva
Lund University, Sweden
Department of experimental Medical science.

Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp

Register here

Label free chemical imaging of fresh, hydrated living tissues and embryos with submicron IR (O-PTIR)

Please join Prof Oxana Klementieva, Lund University, in this two-part webinar based on her recent publication to learn how, for the first time, typical IR spectra and chemical IR images, at submicron resolution were acquired without water interferences in the protein bands, on freshly prepared and hydrated biopsies, tissue slices, and living organisms without compromising sample viability and function.

This webinar will cover;

  • The analysis of fresh mouse brain sections on glass slides, imaging beta-sheet rich amyloid structures
  • Time resolved imaging of living tissues showing evolution of beta-sheets and lipid oxidation
  • How living lung tissue exposed to different levels of IR energy demonstrate no functional impairment
  • Living salamander embryos imaged for lipid droplets, with no impact of measurement on embryo development

Additionally, Dr Mustafa Kansiz, Director of Product Management at Photothermal Spectroscopy Corp, will provide a brief technique overview, covering submicron simultaneous IR+Raman with co-located fluorescence widefield imaging, with advances now delivering sub-500nm IR spatial resolution.

These breakthroughs will be presented in this two-part event, together with a range of application examples, from life sciences, covering live cell lipid metabolism, single cell bacterial measurements with stable isotope labelling to fixed tissues for cell typing.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Submicron simultaneous IR+Raman microscope combines Optical Photothermal Infrared (O-PTIR) spectroscopy with Raman

The mIRage® IR microscope is an innovative new microscopy system uniquely providing sub-micron IR spectroscopy and imaging across a wide variety of applications.
Using a proprietary technique based upon Optical Photothermal IR (O-PTIR) spectroscopy, mIRage®
breaks the diffraction limit of traditional IR spectroscopy and bridges the gap between conventional IR microspectroscopy and nanoscale IR spectroscopy.

2023 interview with Dr. Mustafa Kansiz on the cutting edge technology O-PTIR, and how it will influence the field of infrared spectroscopy.
mIRage product image

Sub-micron IR spectroscopy

Simultaneous sub-micron IR
and Raman spectroscopy

New <500nm IR with simultaneous
Raman and co-located Fluorescence
Photograph of Victoria Beltran
Oxana Klementieva, Ph.D
Associate Professor
Lund University, Sweden
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease

I am very excited about new possibilities that can now be achieved with fluorescence guided OPTIR on the mIRage-LS for biomedical research. The new instrument offers a dream setup for microspectroscopic experiments.

Submicron simultaneous IR+Raman microscope combines Optical Photothermal Infrared (O-PTIR) spectroscopy with Raman

The mIRage® IR microscope is an innovative new microscopy system uniquely providing sub-micron IR spectroscopy and imaging across a wide variety of applications.
Using a proprietary technique based upon Optical Photothermal IR (O-PTIR) spectroscopy, mIRage® 
breaks the diffraction limit of traditional IR spectroscopy and bridges the gap between conventional IR microspectroscopy and nanoscale IR spectroscopy.

Right: 2023 interview with Dr. Mustafa Kansiz on the cutting edge technology O-PTIR, and how it will influence the field of infrared spectroscopy.

mIRage platform applications overview

The advancement of analytical methods and systems are paving the way for innovation in academic, industrial and government sectors. As a result of the fast-paced progress, more research questions are asked that surpass the limits of these technologies. The mIRage IR Microscope is now answering these questions using Optical Photothermal IR (O-PTIR) spectroscopy, as well as IR+Raman – simultaneous submicron IR and Raman microscopy. With more chemical characterization requirements being met, mIRage is ushering in the next generation of applications and technology developments in numerous industries.

mIRage IR microscope

New <500nm IR with simultaneous
Raman and co-located fluorescence
mIRage product image

Sub-micron IR spectroscopy

Simultaneous sub-micron IR
and Raman spectroscopy

Photograph of Victoria Beltran

Oxana Klementieva, Ph.D

Associate Professor
Lund University, Sweden
Principal investigator at MultiPark
Multidisciplinary research focused on Parkinson´s disease

I am very excited about new possibilities that can now be achieved with fluorescence guided OPTIR on the mIRage-LS for biomedical research. The new instrument offers a dream setup for microspectroscopic experiments.

mIRage platform applications overview

The advancement of analytical methods and systems are paving the way for innovation in academic, industrial and government sectors. As a result of the fast-paced progress, more research questions are asked that surpass the limits of these technologies. The mIRage IR Microscope is now answering these questions using Optical Photothermal IR (O-PTIR) spectroscopy, as well as IR+Raman – simultaneous submicron IR and Raman microscopy. With more chemical characterization requirements being met, mIRage is ushering in the next generation of applications and technology developments in numerous industries.

Sub-micron IR spectroscopy with simultaneous Raman microscopy and co-located fluorescence microscopy

Illustration showing O-PTIR analysis of a fingerprint for sub micron particles of TNT

Publications

Many of our customer publications highlight breakthroughs in science detailed in high impact publications. These breakthroughs cover a wide range of scientific research from the frontiers of bioimaging, to sub-micron IR measurement of microplastics, and achieving single molecule imaging resolution with combined SERS/SIERA measurement.

Webinars

Webinars based on data published by researchers at various institutions using the mIRage microscope.

Webinars

Webinars based on data published by researchers at various institutions using the mIRage microscope.

Life Science

Live cell, tissues, bacteria

Microplastics

Environmental bioplastics

Failure analysis

Organic contaminants

Polymers

Live cell, tissues, bacteria

Products
Techniques

Sub-micron IR spectroscopy with simultaneous Raman microscopy and co-located fluorescence microscopy

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Photothermal Spectroscopy Corp

325 Chapala Street
Santa Barbara, CA 93101

Phone: (805) 845-6568
Email: info [at] photothermal.com