Webinars

Live cells, tissues and single cell bacterial analysis using submicron IR and simultaneous Raman spectroscopy

Thursday, December 9

Presenters:

Dr. Christoph Krafft
Leibniz Institute of Photonic Technology, Jena, Germany
Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp

Register here

Join Dr Christoph Krafft, from the Leibniz Institute for Photonic Research, Jena, Germany to hear about his research across a wide range of life science applications from live cells, tissues to single cell bacteria using submicron Optical Photothermal Infrared (O-PTIR) spectroscopy
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview together a range of application examples in this two part event.
A summary of the webinar includes;

  • Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
  • Submicron IR (O-PTIR) and simultaneous Raman applied to life science samples such as:
    – Live cells in water
    – Tissues
    – Single cell bacteria

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Live cells, tissues and single cell bacterial analysis using submicron IR and simultaneous Raman spectroscopy

Thursday, December 9

Presenters:
Dr. Christoph Krafft
Leibniz Institute of Photonic Technology, Jena, Germany

Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

Register here

Join Dr Christoph Krafft, from the Leibniz Institute for Photonic Research, Jena, Germany to hear about his research across a wide range of life science applications from live cells, tissues to single cell bacteria using submicron Optical Photothermal Infrared (O-PTIR) spectroscopy
Additionally, Dr Mustafa Kansiz, Director of Product Management and Marketing at Photothermal Spectroscopy Corp, will provide a brief technique overview together a range of application examples in this two part event.
A summary of the webinar includes;

  • Introduction to submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
  • Submicron IR (O-PTIR) and simultaneous Raman applied to life science samples such as:
    – Live cells in water
    – Tissues
    – Single cell bacteria

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Correlative submicron IR and X-Ray fluorescence for molecular and elemental imaging of neurons

Presenters:

Prof. Oxana Klementieva
Medical Microspectroscopy
Deptartment of Experimental Medical Science
Lund University, Sweden

Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

A summary of the webinar includes;
  • Introduction to submicron IR with the breakthrough technique of O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
  • Combination of sub-micron IR nd Synchrotron X-Ray Fluorescence for molecular and elemental imaging of neurons directly
  • Results show that in primary AD-like neurons, iron cluster co-localise with amyloid-beta sheet protein structures and oxidised lipids

In conjunction with Dr Mustafa Kansiz, who will present an initial overview of the technique with further life science (live cells, tissues and bacteria) application examples and Prof Oxana Klementieva who will detail her recent research publication on this topic, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Correlative submicron IR and X-Ray fluorescence for molecular and elemental imaging of neurons

Presenters:
Prof. Oxana Klementieva
Medical Microspectroscopy
Deptartment of Experimental Medical Science
Lund University, Sweden

Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

A summary of the webinar includes;
  • Introduction to submicron IR with the breakthrough technique of O-PTIR and simultaneous Raman (IR+Raman) microscopy with application examples
  • Combination of sub-micron IR nd Synchrotron X-Ray Fluorescence for molecular and elemental imaging of neurons directly
  • Results show that in primary AD-like neurons, iron cluster co-localise with amyloid-beta sheet protein structures and oxidised lipids

In conjunction with Dr Mustafa Kansiz, who will present an initial overview of the technique with further life science (live cells, tissues and bacteria) application examples and Prof Oxana Klementieva who will detail her recent research publication on this topic, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Accurate microplastics identification from <500nm to mm’s with submicron O-PTIR and simultaneous Raman

Pitfalls, challenges and solutions for robust, artefact-free microplastics analysis

Presenter:
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

Join Dr Mustafa Kansiz, the director of product management and marketing for Photothermal Spectroscopy Corp, in this two part event. In the first part view a webinar on how to conduct robust, reliable and accurate MPs analysis of small (<500nm) to large (mm’s) MPs on the one instrument without encountering any of pitfalls, challenges and artefacts seen with traditional direct FTIR/QCL and Raman microscopy.
In the second part watch, in real-time, a demonstration of submicron O-PTIR and simultaneous Raman microscopy being used to generate consistent and artefact free spectra of MPs <500nm to the very large (mm’s), regardless of particle shape and size.

Part 1: Webinar will cover;

  • Overview of different IR and Raman spectroscopic techniques applied to MPs
  • Recognizing and understanding spectral artefacts/inconsistencies and how they impact accurate MP identification
  • Introduction to Submicron O-PTIR and Simultaneous Raman microscopy
  • How to eliminate these spectral artefacts/inconsistencies for accurate MP identification with O-PTIR
  • Complementary and confirmatory simultaneous IR+Raman spectral collection and spectral searching for improved identification accuracy
    See examples applied to MPs from <500nm to mm’s and how the spectra are reliable and consistent (no artefacts)

Part 2: Live demo:

  • See, in real-time, how easy it is to collect submicron IR and Simultaneous Raman data from MPs, ranging from hundreds of microns to <500nm

Submicron simultaneous IR+Raman for cultural heritage – new findings in a Van Gogh painting

Presenters:
Dr. Victoria Beltran
A-Sense Lab, Uni of Antwerp, Belgium

Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

A summary of the webinar includes;

  • First application of O-PTIR, for submicron IR analysis of cultural heritage pieces
  • Extremely small fragments from a Van Gogh painting, L’Arlésienne (portrait of Madame Ginoux) were analysed
  • Clear detection of geranium lake pigments
  • Complete stratigraphic analysis with O-PTIR, which failed with other state-of-the-art techniques

In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an initial overview of the technique with further application examples, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Submicron simultaneous IR+Raman for cultural heritage – new findings in a Van Gogh painting

Presenters:
Dr. Victoria Beltran
A-Sense Lab, Uni of Antwerp, Belgium

Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

A summary of the webinar includes;

  • First application of O-PTIR, for submicron IR analysis of cultural heritage pieces
  • Extremely small fragments from a Van Gogh painting, L’Arlésienne (portrait of Madame Ginoux) were analysed
  • Clear detection of geranium lake pigments
  • Complete stratigraphic analysis with O-PTIR, which failed with other state-of-the-art techniques

In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an initial overview of the technique with further application examples, we are proud to present this cutting-edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Live demo – submicron O-PTIR and simultaneous Raman (IR+Raman) microscopy webinar, with technique introduction and applications reviews

Presenter:
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp

See first-hand, with a live online instrument demo, how the new breakthrough technique of Optical Photothermal IR (O-PTIR) spectroscopy is revolutionizing the field of IR spectroscopy.
Furthermore, see how it is also allowing for the combination with Raman, to provide for submicron simultaneous IR+Raman microscopy – a world first and only.

Samples to be measured and imaged during the demo include;

  • Single cell bacteria/spores
  • Single eukaryotic cells and tissues
  • Polymer phase dispersion samples
  • Particulates (microplastics)

O-PTIR breaks all the known limitations and issues with conventional FTIR/QCL microscopy with a summary of capabilities listed below;

  • Ability to perform simultaneous, submicron IR+Raman microscopy (same spot, same time, same resolution)
  • Submicron (~500nm) IR or (IR+Raman) spatial resolution
  • No IR dispersive scatter artefacts (Mie scatter)
  • Easy-to-use reflection mode (non-contact), delivering high quality spectra that are fully comparable to FTIR transmission data
  • Single frequency (wavenumber) imaging, no more having to collect slow hyperspectrals
  • Little to no sample prep, measure from 100nm to >10mm in thickness, rough or smooth.
  • Zero fluorescence interference for the IR, regardless of laser wavelength or sample
  • Excellent spectral sensitivity in ~1sec
  • No laser sample damage or phototoxicity (laser powers <100mW)

Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, will present an overview of the technique, with examples of applications from life sciences, polymer research, particulates (microplastics), industrial failure analysis and more, before switching to a live online instrument demo.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar

Sub-cellular resolution simultaneous IR+Raman (O-PTIR) imaging for biomedical applications

Dr. Rohith Reddy
Assistant Professor, Department of Electronic and Computer Engineering
University of Houston

Dr. Mustafa Kansiz
Director of Product Management
and Marketing
Photothermal Spectroscopy Corp

O-PTIR and submicron simultaneous IR+Raman technique overview

O-PTIR imaging for spectral-histopathology of ovarian tissues

Demonstration of 20x improvement of spatial resolution vs FTIR for tissues

Bone disorders and collagen deposition studied with O-PTIR

Other examples of IR+Raman, live cell imaging, single cell bacteria, microplastics etc

Asst Prof Rohith Reddy, will discuss how the combination of biochemically relevant molecular information along with morphology makes Mid-Infrared Spectroscopic Imaging (MIRSI) especially useful in medical applications such as cancer research. Early diagnosis of cancers, like ovarian cancer, is essential for improving survival. To automate the process of disease diagnosis, we perform MIRSI imaging followed by machine learning. However, this requires data of high signal-to-noise ratio and resolution. In this presentation, we use O-PTIR with an order of magnitude higher resolution relative to FT-IR imaging and present histopathology results for ovarian tissue. Additionally, bone disorders such as osteosclerosis and collagen deposition have spectroscopic signatures that can also e identified using MIRSI. We present high-resolution O-PTIR imaging data and results from studies of challenging clinical bone samples.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique, including simultaneous sub-micron IR+Raman microscopy with further life science research examples (live cell imaging, single cell bacteria etc) we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Sub-cellular resolution simultaneous IR+Raman (O-PTIR) imaging for biomedical applications

Thursday, May 27

Presenters:
Dr. Rohith Reddy
Assistant Professor, Deptartment of Electronic and Computer Engineering, University of Houston

Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp

O-PTIR and submicron simultaneous IR+Raman technique overview

O-PTIR imaging for spectral-histopathology of ovarian tissues

Demonstration of 20x improvement of spatial resolution vs FTIR for tissues

Bone disorders and collagen deposition studied with O-PTIR

Other examples of IR+Raman, live cell imaging, single cell bacteria, microplastics etc

Asst Prof Rohith Reddy, will discuss how the combination of biochemically relevant molecular information along with morphology makes Mid-Infrared Spectroscopic Imaging (MIRSI) especially useful in medical applications such as cancer research. Early diagnosis of cancers, like ovarian cancer, is essential for improving survival. To automate the process of disease diagnosis, we perform MIRSI imaging followed by machine learning. However, this requires data of high signal-to-noise ratio and resolution. In this presentation, we use O-PTIR with an order of magnitude higher resolution relative to FT-IR imaging and present histopathology results for ovarian tissue. Additionally, bone disorders such as osteosclerosis and collagen deposition have spectroscopic signatures that can also e identified using MIRSI. We present high-resolution O-PTIR imaging data and results from studies of challenging clinical bone samples.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique, including simultaneous sub-micron IR+Raman microscopy with further life science research examples (live cell imaging, single cell bacteria etc) we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Live single cell analysis with simultaneous submicron IR+Raman spectroscopy:

Life science applications of O-PTIR, from tissues, single bacteria to live cells

Presenters:
Prof. Peter Gardner
Chemical Engineering and Analytical Science, Manchester University, UK

Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp

In this webinar, Prof Peter Gardner (Manchester University, UK) will present results from their recent and first published study on live (and fixed) cell analysis with simultaneous submicron IR+Raman microscopy with wide spectral coverage using two pump lasers (QCL and OPO).
Using this experimental configuration, all biologically relevant IR vibrations are probed, with further vibration complementarity provided by the concomitant Raman data, generating a full vibrational spectroscopic profile. Pancreatic and breast cancer cell lines are used as model cells to demonstrate these exciting new capabilities.
These combined modalities are shown to be able to analyze subcellular structures in both fixed and, more importantly, live cells under aqueous conditions. We show that the protein secondary structure and lipid-rich bodies can be identified on the submicron scale.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique with further life science research examples (tissues, single cell bacteria etc) we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Live single cell analysis with simultaneous submicron IR+Raman spectroscopy:

Life science applications of O-PTIR, from tissues, single bacteria to live cells

Presenters:
Prof. Peter Gardner
Chemical Engineering and Analytical Science, Manchester University, UK

Dr. Mustafa Kansiz
Director of Product Management and Marketing, Photothermal Spectroscopy Corp

In this webinar, Prof Peter Gardner (Manchester University, UK) will present results from their recent and first published study on live (and fixed) cell analysis with simultaneous submicron IR+Raman microscopy with wide spectral coverage using two pump lasers (QCL and OPO).
Using this experimental configuration, all biologically relevant IR vibrations are probed, with further vibration complementarity provided by the concomitant Raman data, generating a full vibrational spectroscopic profile. Pancreatic and breast cancer cell lines are used as model cells to demonstrate these exciting new capabilities.
These combined modalities are shown to be able to analyze subcellular structures in both fixed and, more importantly, live cells under aqueous conditions. We show that the protein secondary structure and lipid-rich bodies can be identified on the submicron scale.
In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, who will present an overview of the technique with further life science research examples (tissues, single cell bacteria etc) we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Single and intra-cell bacterial IR spectroscopy:

Life science applications of O-PTIR, from tissues to live cells and single cell bacteria

Available for viewing

Presenters:
Prof. Roy Goodacre
Department of Biochemistry and Systems Biology
University of Liverpool

Dr. Mustafa Kansiz
Director of Product Management
Photothermal Spectroscopy Corp

Illustration of O-PTIR and R+Raman used for life science applications from tissues, to single bacterial cells
In this webinar, we will show how submicron simultaneous Optical-Photothermal IR (O-PTIR) spectroscopy and Raman microscopy (IR+Raman) is being used and published in life science applications, from tissues, to cells and even single bacterial cells.

Prof Roy Goodacre (Uni Liverpool, UK) will present results from his recent publication on stable isotope labelled bacteria, studied with single cell O-PTIR to reveal insights into bacterial metabolism, not only as communities, but also interactions between microorganisms. This presents a significant advance as most studies have focused on evaluating communities of cells, due to the poor spatial resolution achieved by classical infrared microspectrometers and, to date, there is no study evaluating the incorporation of labelled compounds by bacteria at single cell levels using infrared spectroscopy.

In conjunction with Dr Mustafa Kansiz, Director of Product Management and Marketing at PSC, we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Collagen orientation, fiber to submicron fibril life science applications of O-PTIR, from tissues to single cells and bacteria

Available for viewing

Presenters:
Prof. Kathy Gough
Dept of Chemistry, University of Manitoba, Canada
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.

In this webinar, we will show how, submicron simultaneous Optical-Photothermal IR (O-PTIR) spectroscopy and Raman microscopy (IR+Raman) is being used and published in life science applications, from tissues, to cells and even single bacterial cells. Prof Kathy Gough (Uni Manitoba, Canada) will present results from her recent publication on collagen, tendon and fibril analysis with O-PTIR, where polarized IR light was used to gain insight into hierarchical molecular orientation. Spectra and images were obtained from sections of intact oriented tendon (on CaF2 and glass) and individual fibrils of ~500 nm diameter, to yield the first confirmatory and complementary polarized data on a biopolymer. The Amide I and II bands in fibril spectra were narrower than those from the intact tendon, whilst both relative intensities and band shapes were altered. These spectra represent reliable profiles for normal collagen type I fibrils under polarized IR light, and can serve as a benchmark for the study of collagenous tissues.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Collagen orientation, fiber to submicron fibril life science applications of O-PTIR, from tissues to single cells and bacteria

Available for viewing

Presenters:
Prof. Kathy Gough
Dept of Chemistry, University of Manitoba, Canida
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.

In this webinar, we will show how, submicron simultaneous Optical-Photothermal IR (O-PTIR) spectroscopy and Raman microscopy (IR+Raman) is being used and published in life science applications, from tissues, to cells and even single bacterial cells. Prof Kathy Gough (Uni Manitoba, Canada) will present results from her recent publication on collagen, tendon and fibril analysis with O-PTIR, where polarized IR light was used to gain insight into hierarchical molecular orientation. Spectra and images were obtained from sections of intact oriented tendon (on CaF2 and glass) and individual fibrils of ~500 nm diameter, to yield the first confirmatory and complementary polarized data on a biopolymer. The Amide I and II bands in fibril spectra were narrower than those from the intact tendon, whilst both relative intensities and band shapes were altered. These spectra represent reliable profiles for normal collagen type I fibrils under polarized IR light, and can serve as a benchmark for the study of collagenous tissues.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting-edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Forensic paint analysis with simultaneous submicron O-PTIR and Raman microspectroscopy

Available for viewing

Presenters:
Assoc. Prof. Brooke Kammrath
Forensic Science Department, University of New Haven
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Paint evidence can provide valuable associative information for crimes involving vehicular accidents and home invasions. The complex chemistry of paint is thoroughly interrogated with vibrational microspectroscopy, with results that are used for its classification and comparison. Traditional IR microscopy is frequently used to identify binders, some pigments and additives, but suffers from limited spatial resolution (less than 10 µm) and difficult sample preparation. On the other hand, Raman microspectroscopy affords the additional ability to identify colored pigments at high spatial resolution, thus providing complimentary information, but can often suffer from severe fluorescence interference, especially with coloured samples.

In this webinar, we will show how for the first time, submicron simultaneous Optical-Photothermal IR (O-PTIR) spectroscopy and Raman microscopy (IR+Raman) can be used to overcome many of these traditional limits and be used for non-contact, far-field submicron paint cross-sections to yield high quality spectra that are easily searchable and interpretable. Furthermore, we demonstrate how combining this analysis with simultaneous Raman, provides for a more thorough chemical characterisation of the paint cross-section, providing rich information on their organic and inorganic composition at high spatial resolution (less than 1 µm).
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.

Particle analysis with submicron IR spectroscopy and simultaneous Raman – Microplastics, fibers and atmospheric aerosols

Available for viewing

Presenters:
Asst. Prof Andrew Ault
Department of Chemistry, University of Michigan
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.

Asst. Prof. Andrew Ault and co-workers demonstrate the novel application of submicron IR and simultaneous Raman for the physiochemical analysis of atmospheric aerosols with aerodynamic diameters <400nm. Vibrational spectroscopy (IR and Raman) has great potential for atmospheric aerosol characterization, but the diffraction limit of traditional IR microscopy (~10 microns) makes this impossible. In their recent publication, the team has shown for the first time, how Optical-Photothermal IR (O-PTIR) spectroscopy can be used for non-contact, far-field submicron particle measurements to yield high spectral spectra that are easily searchable and interpretable. Furthermore, they demonstrate how combining this analysis with simultaneous Raman provide for a more thorough chemical characterisation of the atmospheric aerosols, proving a rich information on their organic and inorganic composition.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.

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Particle analysis with submicron IR spectroscopy and simultaneous Raman – Microplastics, fibers and atmospheric aerosols

Available for viewing

Presenters:
Asst. Prof Andrew Ault
Department of Chemistry, University of Michigan
Dr. Mustafa Kansiz
Director of Product Management and Marketing
Photothermal Spectroscopy Corp.

Asst. Prof. Andrew Ault and co-workers demonstrate the novel application of submicron IR and simultaneous Raman for the physiochemical analysis of atmospheric aerosols with aerodynamic diameters <400nm. Vibrational spectroscopy (IR and Raman) has great potential for atmospheric aerosol characterization, but the diffraction limit of traditional IR microscopy (~10 microns) makes this impossible. In their recent publication, the team has shown for the first time, how Optical-Photothermal IR (O-PTIR) spectroscopy can be used for non-contact, far-field submicron particle measurements to yield high spectral spectra that are easily searchable and interpretable. Furthermore, they demonstrate how combining this analysis with simultaneous Raman provide for a more thorough chemical characterisation of the atmospheric aerosols, proving a rich information on their organic and inorganic composition.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.
The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Submicron non-contact IR spectroscopy and simultaneous Raman in life sciences, microplastics, polymers, contaminant ID and more

Available for viewing

Presenters:
Dr. Ji-Xin Cheng
Moustakas Chair Professor of Photonics, Boston University
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Dr. Kansiz will introduce the new breakthrough technique, Optical Photothermal IR (O-PTIR) Spectroscopy, an optical IR spectroscopy technique which provides for the first time ever;
a) submicron resolution
b) high quality absorption spectra in non-contact reflection mode without scatter/dispersion artifacts.
c) Water compatible IR measurements

O-PTIR and IR+Raman applications will be discussed in a broad range of fields such as life sciences, particulates/microplastics, polymers and failure/defect analysis.

Professor Ji-Xin Cheng of Boston University is the co-inventor of O-PTIR. He is one of the world’s leading vibrational spectroscopy researchers, having previously co-invented CARS, while doing his post-doctoral work with Prof Sunny Xie of Harvard. Prof Cheng has recently received several prestigious awards for his research including the Lippincott Award and the Pittcon Spectroscopy Award.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Submicron non-contact IR spectroscopy and simultaneous Raman in life sciences, microplastics, polymers, contaminant ID and more

Available for viewing

Presenters:
Dr. Ji-Xin Cheng
Moustakas Chair Professor of Photonics, Boston University
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

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Dr. Kansiz will introduce the new breakthrough technique, Optical Photothermal IR (O-PTIR) Spectroscopy, an optical IR spectroscopy technique which provides for the first time ever;
a) submicron resolution
b) high quality absorption spectra in non-contact reflection mode without scatter/dispersion artifacts.
c) Water compatible IR measurements

O-PTIR and IR+Raman applications will be discussed in a broad range of fields such as life sciences, particulates/microplastics, polymers and failure/defect analysis.

Professor Ji-Xin Cheng of Boston University is the co-inventor of O-PTIR. He is one of the world’s leading vibrational spectroscopy researchers, having previously co-invented CARS, while doing his post-doctoral work with Prof Sunny Xie of Harvard. Prof Cheng has recently received several prestigious awards for his research including the Lippincott Award and the Pittcon Spectroscopy Award.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Bioplastics characterization – Polymer applications using sub-micron simultaneous IR+Raman spectroscopy

Available for viewing

Presenters:
Dr. Isao Noda
Chief Science Officer and Senior VP of Innovation at Danimer Scientific
Affiliated Professor at Science and Engineering at the University of Delaware

Dr. Curtis Marcott
Senior Partner at Light Light Solutions
Danimer Scientific, Athens, Georgia
Deptartment of Materials, University of Delaware

Dr. Isao Noda and co-workers explore the spatial chemical distributions at the interface of a bioplastic (PHA/PLA) laminate at previously unattained levels of spatial resolution of a few hundred nm, Using O-PTIR coupled with Raman (IR+Raman), new insights at the interfacial boundary of PHA and PLA are reveal. Previously thought to be immiscible, using 2-D Correlation Spectroscopy (2DCOS) data analysis, a surprising degree of polymer mixing together with decreased crystallinity at the interface is revealed, thus potentially explaining the high compatibility of this two bioplastics.
In conjunction with Dr Curtis Marcott, who will introduce the breakthrough technique of O-PTIR and through discussion of a range of polymer application examples, will illustrate the advantages of O-PTIR.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Bioplastics characterization – Polymer applications using sub-micron simultaneous IR+Raman spectroscopy

Available for viewing

Presenters:
Dr. Isao Noda
Chief Science Officer and Senior VP of Innovation at Danimer Scientific
Affiliated Professor at Science and Engineering at the University of Delaware

Dr. Curtis Marcott
Senior Partner at Light Light Solutions
Danimer Scientific, Athens, Georgia
Deptartment of Materials, University of Delaware

Dr. Isao Noda and co-workers explore the spatial chemical distributions at the interface of a bioplastic (PHA/PLA) laminate at previously unattained levels of spatial resolution of a few hundred nm, Using O-PTIR coupled with Raman (IR+Raman), new insights at the interfacial boundary of PHA and PLA are reveal. Previously thought to be immiscible, using 2-D Correlation Spectroscopy (2DCOS) data analysis, a surprising degree of polymer mixing together with decreased crystallinity at the interface is revealed, thus potentially explaining the high compatibility of this two bioplastics.
In conjunction with Dr Curtis Marcott, who will introduce the breakthrough technique of O-PTIR and through discussion of a range of polymer application examples, will illustrate the advantages of O-PTIR.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Amyloid aggregates in neurons – Life science applications using submicron simultaneous IR and Raman microscopy
(Publication chosen for cover of Advanced Science, Mar 18, 2020)

Available for viewing

Presenters:
Dr. Oxana Klementieva
Assistant Professor in Neurobiology
Medical Microspectroscopy research group Lund University, Sweden
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Dr Oxana Klementieva and co-workers identifying amyloid-beta aggregates directly in neurons (neurites an dendritic spines) at the subcellular (submicron) level using Optical Photothermal Infrared (O-PTIR) imaging (mIRage submicron Infrared Microscope). They provided a glimpse of what might occur at earlier stages of Alzheimer’s Disease pathology showing that in neurons, amyloid aggregates can have structural polymorphism, which may trigger various mechanisms of Alzheimer’s disease progression.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Amyloid aggregates in neurons – Life science applications using submicron simultaneous IR and Raman microscopy

(Publication chosen for cover of Advanced Science, Mar 18, 2020)

Available for viewing

Presenters:
Dr. Oxana Klementieva
Assistant Professor in Neurobiology
Medical Microspectroscopy research group Lund University, Sweden
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Dr Oxana Klementieva and co-workers identifying amyloid-beta aggregates directly in neurons (neurites an dendritic spines) at the subcellular (submicron) level using Optical Photothermal Infrared (O-PTIR) imaging (mIRage submicron Infrared Microscope). They provided a glimpse of what might occur at earlier stages of Alzheimer’s Disease pathology showing that in neurons, amyloid aggregates can have structural polymorphism, which may trigger various mechanisms of Alzheimer’s disease progression.
In conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC we are proud to present this cutting edge webinar.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Life science applications using novel submicron simultaneous IR and Raman microscopy – A new paradigm in vibrational spectroscopy

Available for viewing

Presenters:
Prof. Ji-Xin Cheng 
Moustakas Professor in Photonics and Optoelectronics, Professor of ECE, BME, Chemistry & Physics, Boston University Photonics Center
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Professor Ji-Xin Cheng of Boston University Photonics Center, author of over 230 peer-reviewed papers, co-inventor of CARS microscopy and pioneer in the field of O-PTIR applied to life science systems, in conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC are proud to present this webinar.

This webinar will cover the invention, various strategies of instrumentation, broad applications and commercialization of far-field Optical Photothermal IR (O-PTIR) microscopy, presenting both scanning-based and wide-field approaches with various life science applications. Integration with Raman spectroscopy will also be highlighted.

Learn how now, for the first-time live cells can be measured in water, with submicron spatial resolution, with IR spectral information, allowing for cellular metabolism and drug uptake studies for example.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Life science applications using novel submicron simultaneous IR and Raman microscopy – A new paradigm in vibrational spectroscopy

Available for viewing

Presenters:
Prof. Ji-Xin Cheng 
Moustakas Professor in Photonics and Optoelectronics, Professor of ECE, BME, Chemistry & Physics, Boston University Photonics Center
Dr. Mustafa Kansiz
Director of Product Management, Photothermal Spectroscopy Corp

Professor Ji-Xin Cheng of Boston University Photonics Center, author of over 230 peer-reviewed papers, co-inventor of CARS microscopy and pioneer in the field of O-PTIR applied to life science systems, in conjunction with Dr Mustafa Kansiz, Director of Product Management at PSC are proud to present this webinar.

This webinar will cover the invention, various strategies of instrumentation, broad applications and commercialization of far-field Optical Photothermal IR (O-PTIR) microscopy, presenting both scanning-based and wide-field approaches with various life science applications. Integration with Raman spectroscopy will also be highlighted.

Learn how now, for the first-time live cells can be measured in water, with submicron spatial resolution, with IR spectral information, allowing for cellular metabolism and drug uptake studies for example.

The webinar will be recorded for later on-demand viewing with opportunities to ask questions during and after the webinar.

Simultaneous IR+Raman and database searching for more confident unknown ID

Available for viewing

Speakers:
Dr. Curtis Marcott, Senior Partner, Light Light Solutions
Dr. Gregory Banik, General Manager, Bio-Rad Laboratories, Inc.

Join us for a webinar that discusses a unique approach for complementary and confirmatory analysis using an Optical Photothermal infrared (O-PTIR) technology (mIRage+R Infrared and Raman microscope) for simultaneous measurement of IR and Raman spectra and software (BioRad, KnowItAll) for simultaneous, multi-technique searching of IR and Raman spectral databases.

This new approach dramatically improves the identification accuracy of results compared to single technique measurement and database searching.

Simultaneous IR+Raman and database searching for more confident unknown ID

Available for viewing

Speakers:
Dr. Curtis Marcott, Senior Partner, Light Light Solutions
Dr. Gregory Banik, General Manager, Bio-Rad Laboratories, Inc.

Join us for a webinar that discusses a unique approach for complementary and confirmatory analysis using an Optical Photothermal infrared (O-PTIR) technology (mIRage+R Infrared and Raman microscope) for simultaneous measurement of IR and Raman spectra and software (BioRad, KnowItAll) for simultaneous, multi-technique searching of IR and Raman spectral databases.

This new approach dramatically improves the identification accuracy of results compared to single technique measurement and database searching.

Identifying organic contaminants with breakthrough submicron IR and simultaneous Raman microscopy

Available for viewing

Presenters:
Dr. Mustafa Kansiz, Photothermal Spectroscopy Corp
Dr. Dennis WallsDupont

Successfully identifying contaminants is a critical step in ensuring that both product quality and yield are maintained during failure analysis. With ever stricter control standards and the shrinking size of high-tech products, confidently identifying smaller contaminants is becoming increasingly important. While high spatial resolution techniques exist for elemental and inorganic analysis, identification of organic contamination at the micron and submicron scale has been challenging.

Identifying organic contaminants with breakthrough submicron IR and simultaneous Raman microscopy

Available for viewing

Presenters:
Dr. Mustafa Kansiz, Photothermal Spectroscopy Corp
Dr. Dennis WallsDupont

Successfully identifying contaminants is a critical step in ensuring that both product quality and yield are maintained during failure analysis. With ever stricter control standards and the shrinking size of high-tech products, confidently identifying smaller contaminants is becoming increasingly important. While high spatial resolution techniques exist for elemental and inorganic analysis, identification of organic contamination at the micron and submicron scale has been challenging.

Simultaneous submicron IR and Raman microscopy – A World first

Available for viewing

Presenter:
Dr. Mustafa Kansiz 
Director of Product Management
Photothermal Spectroscopy Corp

O-PTIR surpasses accepted limitations of IR microscopy, ushering in a new era of analytical capabilities and problem solving. Coupled with simultaneous Raman microscopy, IR+Raman is now finally possible! This webinar will discuss O-PTIR and its major benefits across a range of application areas, including defect and failure analysis, polymers, materials, life science, pharmaceuticals and forensics.

Simultaneous submicron IR and Raman microscopy – A World first

Available for viewing

Presenter:
Dr. Mustafa Kansiz 
Director of Product Management
Photothermal Spectroscopy Corp

O-PTIR surpasses accepted limitations of IR microscopy, ushering in a new era of analytical capabilities and problem solving. Coupled with simultaneous Raman microscopy, IR+Raman is now finally possible! This webinar will discuss O-PTIR and its major benefits across a range of application areas, including defect and failure analysis, polymers, materials, life science, pharmaceuticals and forensics.

O-PTIR: Solving two of the biggest problems in IR spectroscopy

Achieving sub-micron IR spectroscopy using a non-contact optical technique

Available for viewing

Presenters:
Dr. Curtis Marcott,
 Senior Partner, Light Light Solutions
Dr. Craig Prater, CTO, Photothermal Spectroscopy Corp

Two of the biggest problems in IR spectroscopy are poor spatial resolution, and sample preparation requirements to avoid traditional ATR contact-related limitations. Photothermal Spectroscopy Corp is overcoming both of these limitations with a breakthrough technology based on optical photothermal IR spectroscopy (O-PTIR). This webinar discusses O-PTIR and its major benefits in the field of IR spectroscopy, including:

  • Sub-micron spatial resolution
  • Transmission FTIR quality spectra in reflection mode on thick samples
  • Non-contact optical technique with none of the limitations of ATR
  • Spatial resolution and sample preparation advantages found in Raman technology, with IR sensitivity
  • Works on any sample prepared for IR or Raman spectroscopy
O-PTIR: Solving two of the biggest problems in IR spectroscopy

Achieving sub-micron IR spectroscopy using a non-contact optical technique

Available for viewing

Presenters:
Dr. Curtis Marcott,
 Senior Partner, Light Light Solutions
Dr. Craig Prater, CTO, Photothermal Spectroscopy Corp

Two of the biggest problems in IR spectroscopy are poor spatial resolution, and sample preparation requirements to avoid traditional ATR contact-related limitations. Photothermal Spectroscopy Corp is overcoming both of these limitations with a breakthrough technology based on optical photothermal IR spectroscopy (O-PTIR). This webinar discusses O-PTIR and its major benefits in the field of IR spectroscopy, including:

  • Sub-micron spatial resolution
  • Transmission FTIR quality spectra in reflection mode on thick samples
  • Non-contact optical technique with none of the limitations of ATR
  • Spatial resolution and sample preparation advantages found in Raman technology, with IR sensitivity
  • Works on any sample prepared for IR or Raman spectroscopy