Publications using the mIRage microscope techniques of O-PTIR and IR plus Raman (IR+Raman)

Our list of publications using the mIRage microscope techniques of O-PTIR and IR+Raman have been rapidly growing. Look through these interesting papers for creative uses in research and ways you might use them in your own projects.

Unique IR+Raman and O-PTIR capabilities are being used in the high-volume, high-value, memory storage, electronics, and display industries

Illustration of publications using the mIRage microscope with the IR+Raman technique for identifying computer hard drive contamination
Optical photothermal infrared microspectroscopy with simultaneous Raman – a new non-contact failure analysis technique for electronics
O-PTIR identified pink particles in a fragment from a historical painting. μSR-FTIR and μRaman were not able to unambiguously identify this material.
Image of data from Publications using the mIRage microscope with O-PTIR and IR+Raman techniques to identify the material in microplastic composites
O-PTIR spectra collected at each point and reference spectrum of freshly synthetized geranium lake obtained by the same technique.

In a new finding, amyloid protein aggregates were detected at the subcellular level, along the neurites and in dendritic spines

Data image from publications using the mIRage microscope to detect amyloid protein aggregates in dendritic spines
Super‐resolution infrared imaging of polymorphic amyloid aggregates directly in neurons

Publication list

Title of publicationAuthor and organizationJournalApplicationTechniqueYear
Optical photothermal infrared microspectroscopy discriminates for the first time different types of lung cells on histopathology glass slides
https://pubs.acs.org/doi/10.1021/acs.analchem.1c00309		Kansiz, M. et al.
Photothermal Spectroscopy Corp		Analytical ChemistryLife Science
Cell differentiation		O-PTIR
2021
Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
https://doi.org/10.1038/s41377-021-00590-x		Gustavsson, N. et al.
Medical Microspectroscopy, Department of Experimental Medical Science, Lund University, Sweden		Light: Science & ApplicationsBiomedical
Neurons		O-PTIR
2021
Nanoscale analysis of historical paintings by means of O-PTIR spectroscopy: The identification of the organic particles in L’Arlésienne (portrait of Madame Ginoux) by Van Gogh
https://doi.org/10.1002/anie.202106058		Beltran, V. et al
AXES research group, University of Antwerp, Belgium		Angewandte ChemieCultural HeritageO-PTIR
2021
Multiple antibiotics distribution in drinking water and their co-absorption behaviors by different size fractions of natural particles
https://doi.org/10.1016/j.scitotenv.2021.145846		Zhao, P. et al
Department of Environmental Engineering, School of Environmental Science and Engineering, Tianjin University, China
Science of The Total EnvironmentEnvironmental
Microplastics/Microplastics		O-PTIR
2021
Analysis of fixed and live single cells using optical photothermal infrared with concomitant Raman spectroscopy
https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04846		Spadea, A. et al
University of Manchester, UK		Analytical ChemistryBiomedical
Fixed and live cells		O-PTIR
IR+Raman
OPO
Transmission mode
2021
Imaging isotopically labeled bacteria at the single-cell level using high-resolution optical infrared photothermal spectroscopy
https://pubs.acs.org/doi/10.1021/acs.analchem.0c03967		Lima C. et al
Institute of Systems, Molecular and Integrative Biology, University of Liverpool, UK		Analytical ChemistryBiomedical
Bacteria		O-PTIR
2021
Resolving nanocomposite interfaces via simultaneous submicrometer optical-photothermal infrared-raman microspectroscopy
https://onlinelibrary.wiley.com/doi/abs/10.1002/admi.202001720		Alexander J. Wang et al
Advanced Manufacturing Institute, University of Houston		Advanced Material InterfacesMaterials science
Nanocomposites		O-PTIR
IR+Raman
2021
Sub-micron, non-contact, super-resolution infrared microspectroscopy for microelectronics contamination and failure analyses
https://ieeexplore.ieee.org/document/9261071		Lo, M. et. al.
Photothermal Spectroscopy Corp.
2020 IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA)Contamination
Failure analysis		O-PTIR
2020
Orientation matters: Polarization dependent IR spectroscopy of collagen from intact tendon down to the single fibril Level
https://www.mdpi.com/1420-3049/25/18/4295		Gough, K. M. et al
Department of Chemistry, University of Manitoba, Canada		MoleculesBiomedical
Collagen		O-PTIR
Polarized IR
2020
Microplastic pollution in deep-sea sediments from the Great Australian Bight
https://www.frontiersin.org/articles/10.3389/fmars.2020.576170		Barret J. et al.
CSIRO, Oceans and Atmosphere, Hobart, TAS, Australia		Frontiers in Marine ResearchEnvironmental
Microplastics		O-PTIR
2020
Detection of high explosive materials within fingerprints by means of optical-photothermal infrared spectromicroscopy
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c00938		Banas, A. et al
Singapore Synchrotron Light Source, National University of Singapore		Analytical ChemistryForensics
Explosives		O-PTIR
2020
Simultaneous optical photothermal infrared (O-PTIR) and Raman spectroscopy of submicrometer atmospheric particles
https://pubs.acs.org/doi/10.1021/acs.analchem.0c01495		Olson, N. et al
University of Michigan		Analytical ChemistryMicroparticles
Aerosols		O-PTIR
IR+Raman
2020
Optical photothermal infrared microspectroscopy with simultaneous Raman – a new non-contact failure analysis technique for identification of <10 μm organic contamination in the hard drive and other electronics industries
https://doi.org/10.1017/S1551929520000917		Kansiz, M. et al
Photothermal Spectroscopy Corp and Seagate Technology		Microscopy TodayContamination
Failure analysis		O-PTIR
IR+Raman
2020
Two-dimensional correlation analysis of highly spatially resolved simultaneous IR and Raman spectral imaging of bioplastics composite using optical photothermal infrared and Raman spectroscopy
https://doi.org/10.1016/j.molstruc.2020.128045		Marcott, C. et al
University of Delaware		The Journal of Molecular StructurePolymers
Laminates
2DCOS		O-PTIR
IR+Raman
2020
Super resolution correlative far-field submicron simultaneous IR and raman microscopy: a new paradigm in vibrational spectroscopy
https://doi.org/10.1117/12.2565489		Kansiz, M. et al
Photothermal Spectroscopy Corp		Advanced Chemical Microscopy for Life Science and Translational MedicineAnalytical techniqueO-PTIR
IR+Raman
2020
Super-resolution infrared imaging of polymorphic amyloid aggregates directly in neurons
https://doi.org/10.1002/advs.201903004		Klementieva, O. et al
Lund University		Advanced ScienceBiomedical
Neurons
Fixed		O-PTIR
2020
Spontaneous formation of 2D-3D heterostructures on the edges of 2D Ruddlesden-Popper hybrid perovskite crystals
https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.0c00419		Qin, Z. et al
Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, and
University of Houston		Chemistry of MaterialsMaterials science
Perovskites		O-PTIR
2020
Bulk to nanometre-scale infrared spectroscopy of pharmaceutical dry powder aerosols
https://doi.org/10.1021/acs.analchem.0c00729		Khanal, D. et al
The University of Sydney		Analytical ChemistryPharmaceuticals
Aerosols		O-PTIR
2020
A global perspective on microplastics
https://doi.org/10.1029/2018JC014719		Hale, R. et al
Virginia Institute of Marine Science		Journal of Geophysical Research: OceanEnvironment microplasticsO-PTIR
IR+Raman
2020
Submicron-resolution polymer orientation mapping by optical photothermal infrared spectroscopy
https://doi.org/10.1080/1023666X.2020.1735851		Baden, N. et al
Nihon Thermal Consulting		International Journal of Polymer Analysis and CharacterizationPolymers, polarizationO-PTIR
2020
Self-formed 2D/3D heterostructure on the edge of 2D ruddlesden-popper hybrid perovskites responsible for intriguing optoelectronic properties and higher cell efficiency
https://arxiv.org/ftp/arxiv/papers/2001/2001.09477.pdf		Qin, Z. et al
Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China		Physics, arXiv: Materials ScienceMaterials science - perovskitesO-PTIR
2020
Evolution of a radical-triggered polymerizing high internal phase emulsion into an open-cellular monolith
https://doi.org/10.1002/macp.201900216		Li, C. et al
Deartment of Polymer Materials, School of Materials Science and Engineering Tongji University		Macromolecular Chemistry and PhysicsPolymersO-PTIR
2019
Advances in infrared microspectroscopy and mapping molecular chemical composition at submicrometer spatial resolution
Spectroscopy: Volume 33, Issue 9, pg 12–17		Reffner, J. et al
John Jay College of Criminal Justice in New York		SpectroscopyPolymers
Fibers
Forensics		O-PTIR
2018
Optical photothermal infrared microspectroscopy discriminates for the first time different types of lung cells on histopathology glass slides
https://pubs.acs.org/doi/10.1021/acs.analchem.1c00309
Author: Kansiz, M. et al.
Institution: Photothermal Spectroscopy Corp
Journal: Analytical Chemistry
Application: Life Science
Cell differentiation
Technique: O-PTIR
Year: 2021
Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
https://doi.org/10.1038/s41377-021-00590-x
Author: Gustavsson, N. et al.
Institution: Medical Microspectroscopy, Department of Experimental Medical Science, Lund University, Sweden
Journal: Light: Science & Applications
Application: Biomedical
Neurons
Technique: O-PTIR
Year: 2021
Nanoscale analysis of historical paintings by means of O-PTIR spectroscopy: The identification of the organic particles in L’Arlésienne (portrait of Madame Ginoux) by Van Gogh
https://doi.org/10.1002/anie.202106058
Author: Beltran, V. et al
Institution: AXES research group, University of Antwerp, Belgium
Journal: Angewandte Chemie
Application: Cultural Heritage
Technique: O-PTIR
Year: 2021
Multiple antibiotics distribution in drinking water and their co-absorption behaviors by different size fractions of natural particles
https://doi.org/10.1016/j.scitotenv.2021.145846
Author: Zhao, P. et al
Institution: Tianjin University, China
Journal: Science of The Total Environment
Application: environmental, microplastics
Technique: O-PTIR
Year: 2021
Analysis of fixed and live single cells using optical photothermal infrared with concomitant Raman spectroscopy
https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04846
Author: Spadea, A. et al
Institution: University of Manchester, UK
Journal: Analytical Chemistry
Application: biomedical, fixed and live cells
Technique: O-PTIR, IR+Raman, OPO, Transmission mode
Year: 2021
Imaging isotopically labeled bacteria at the single-cell level using high-resolution optical infrared photothermal spectroscopy
https://pubs.acs.org/doi/10.1021/acs.analchem.0c03967
Author: Lima C. et al
Organization: University of Liverpool, UK
Journal: Analytical Chemistry
Application: biomedical, bacteria
Technique: O-PTIR
Year: 2021
Resolving nanocomposite interfaces via simultaneous submicrometer optical-photothermal infrared-raman microspectroscopy
https://onlinelibrary.wiley.com/doi/abs/10.1002/admi.202001720
Author: Alexander J. Wang et al
Institution: University of Houston
Journal: Advanced Material Interfaces
Application: materials science, nanocomposites
Technique: O-PTIR, IR+Raman
Year: 2021
Sub-micron, non-contact, super-resolution infrared microspectroscopy for microelectronics contamination and failure analyses
https://ieeexplore.ieee.org/document/9261071
Author: Lo, M. et al
Institution: Photothermal Spectroscopy Corp.
Journal: 2020 IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA)
Application: contamination, failure analysis
Technique: O-PTIR
Year: 2021
Orientation matters: Polarization dependent IR spectroscopy of collagen from intact tendon down to the single fibril Level
https://www.mdpi.com/1420-3049/25/18/4295
Author: Gough, K. M. et al
Institution:University of Manitoba, Canada
Journal: Molecules
Application: biomedical, collagen
Technique: O-PTIR, Polarized IR
Year: 2021
Microplastic pollution in deep-sea sediments from the Great Australian Bight
https://www.frontiersin.org/articles/10.3389/fmars.2020.576170
Author: Barret J. et al
Institution:(CSIRO) Oceans and Atmosphere, Australia
Journal: Frontiers in Marine Research
Application: environmental, microplastics
Technique: O-PTIR
Year: 2020
Detection of high explosive materials within fingerprints by means of optical-photothermal infrared spectromicroscopy
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c00938
Author: Banas, A. et al
Institution:Singapore Synchrotron Light Source
Journal: Analytical Chemistry
Application: forensics, explosives
Technique: O-PTIR
Year: 2020
Simultaneous optical photothermal infrared (O-PTIR) and Raman spectroscopy of submicrometer atmospheric particles
https://pubs.acs.org/doi/10.1021/acs.analchem.0c01495
Author: Olson, N. et al
Institution: University of Michigan
Journal: Analytical Chemistry
Application: microparticles, aerosols
Technique: O-PTIR, IR+Raman
Year: 2020
Optical photothermal infrared microspectroscopy with simultaneous Raman ─ a new non-contact failure analysis technique for identification of <10 µm organic contamination in the hard drive and other electronics industries
https://doi.org/10.1017/S1551929520000917
Author
Author: Kansiz, M. et al
Institution: Photothermal Spectroscopy Corp and Seagate Technology
Journal: Microscopy Today
Application: contamination, failure analysis
Technique: O-PTIR, IR+Raman
Year: 2020
Two-dimensional correlation analysis of highly spatially resolved simultaneous IR and Raman spectral imaging of bioplastics composite using optical photothermal infrared and Raman spectroscopy
https://doi.org/10.1016/j.molstruc.2020.128045
Author: Marcott, C. et al
Institution:University of Delaware
Journal: The Journal of Molecular Structure
Application: polymers, laminates, 2DCOS
Technique: O-PTIR, IR+Raman
Year: 2020
Super resolution correlative far-field submicron simultaneous IR and Raman microscopy: a new paradigm in vibrational spectroscopy
https://doi.org/10.1117/12.2565489
Author: Kansiz, M. et al
Institution:Photothermal Spectroscopy Corp
Journal:Advanced Chemical Microscopy for Life Science and Translational Medicine
Application: analytical technique
Technique: O-PTIR, IR+Raman
Year: 2020
Super-resolution infrared imaging of polymorphic amyloid aggregates directly in neurons
https://doi.org/10.1002/advs.201903004
Author: Klementieva, O. et al
Institution: Lund University
Journal: Advanced Science
Application: biomedical, neurons fixed
Technique: O-PTIR
Year: 2020
Spontaneous formation of 2D-3D heterostructures on the edges of 2D Ruddlesden-Popper hybrid perovskite crystals
https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.0c00419
Author: Qin, Z. et al
Institution: University of Electronic Science and Technology of China,
and University of Houston
Journal: Chemistry of Materials
Application: materials science, perovskites
Technique: O-PTIR
Year: 2020
Bulk to nanometre-scale infrared spectroscopy of pharmaceutical dry powder aerosols
https://doi.org/10.1021/acs.analchem.0c00729
Author
Author: Khanal, D. et al
Institution: The University of Sydney
Journal: Analytical Chemistry
Application: pharmaceuticals, aerosols
Technique: O-PTIR
Year: 2020
A global perspective on microplastics
https://doi.org/10.1029/2018JC014719
Author: Hale, R. et al
Institution: Virginia Institute of Marine Science
Journal: Journal of Geophysical Research: Ocean
Application: environment microplastics
Technique: O-PTIR, IR+Raman
Year: 2020
Submicron-resolution polymer orientation mapping by optical photothermal infrared spectroscopy
https://doi.org/10.1080/1023666X.2020.1735851
Author: Baden, N. et al
Institution: Nihon Thermal Consulting
Journal: International Journal of Polymer Analysis and Characterization
Application: polymers, polarization
Technique: O-PTIR
Year: 2020
Self-formed 2D/3D heterostructure on the edge of 2D ruddlesden-popper hybrid perovskites responsible for intriguing optoelectronic properties and higher cell efficiency
https://arxiv.org/ftp/arxiv/papers/2001/2001.09477.pdf
Author: Qin, Z. et al
Institution: University of Electronic Science and Technology of China
Journal: Physics, arXiv: Materials Science
Application: materials science – perovskites
Technique: O-PTIR
Year: 2020
Evolution of a radical-triggered polymerizing high internal phase emulsion into an open-cellular monolith
https://doi.org/10.1002/macp.201900216
Author: Li, C. et al
Institution:School of Materials Science and Engineering Tongji University
Journal: Macromolecular Chemistry and Physics
Application: polymers
Technique: O-PTIR
Year: 2019
Advances in infrared microspectroscopy and mapping molecular chemical composition at submicrometer spatial resolution
Spectroscopy: Volume 33, Issue 9, pg 12-17
Author: Reffner, J. et al
Institution: John Jay College of Criminal Justice in New York
Journal: Spectroscopy
Application: Polymers, Fibers, Forensics
Technique: O-PTIR
Year: 2018