Publications using the mIRage microscope techniques of O-PTIR and IR plus Raman (IR+Raman)

Our list of publications using the mIRage microscope techniques of O-PTIR and IR+Raman have been rapidly growing. Look through these interesting papers for creative uses in research and ways you might use them in your own projects.

Unique IR+Raman and O-PTIR capabilities are being used in the high-volume, high-value, memory storage, electronics, and display industries.
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Illustration of publications using the mIRage microscope with the IR+Raman technique for identifying computer hard drive contamination

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Found formation of cyclic and branched polysiloxane- or polyimide-containing MNPs in 600nm microplastic particles during steam disinfection of silicone teats

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In a new finding, amyloid protein aggregates were detected at the subcellular level, along the neurites and in dendritic spines
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Data image from publications using the mIRage microscope to detect amyloid protein aggregates in dendritic spines

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Publication list

Title of publication	Author and organization	Journal	Application	Technique	Year
Correlative imaging to resolve molecular structures in individual cells: Substrate validation study for super-resolution infrared microspectroscopy https://doi.org/10.1016/j.nano.2022.102563	Paulus, A., et al Medical Microspectroscopy, Department of Experimental Medical Science, Lund University, Sweden	Nanomedicine	Biomedical Neurons	O-PTIR Fluorescence	2022
Polarization sensitive photothermal mid-infrared spectroscopic imaging of human bone marrow tissue https://doi.org/10.1177%2F00037028211063513	Mankar, R. et al Department of Electrical and Computer Engineering, University of Houston, Houston, TX	Applied Spectroscopy	Life Sciences Tissues - Collagen	O-PTIR IR Polarization	2022
Automated analysis of microplastics based on vibrational spectroscopy: are we measuring the same metrics? http://dx.doi.org/10.1007/s00216-022-03951-6	Dong, M. et al School of Environmental Studies, China University of Geosciences, Wuhan, China	Analytical and Bioanalytical Chemistry	Environmental Microplastics	O-PTIR	2022
Development of a binary digestion system for extraction microplastics in fish and detection method by optical photothermal infrared http://dx.doi.org/10.3389/fmars.2022.845062	Yan, F. et al College of Geography and Environment, Shandong Normal University, Jinan, China	Frontiers in Marine Science	Environmental Microplastics	O-PTIR	2022
Vitamin D and calcium supplementation accelerate vascular calcification in a model of pseudoxanthoma elasticum https://doi.org/10.3390/ijms23042302	Bouderlique, E. et al UMR S 1155, Sorbonne Université, Paris, France	International Journal of Molecular Sciences	Life Sciences Arterial Calcifications	O-PTIR	2022
Novel optical photothermal infrared (O-PTIR) spectroscopy for the noninvasive characterization of heritage glass-metal objects https://doi.org/10.1126/sciadv.abl6769	Marchetti, A. et al AXES Research Group, University of Antwerp, Belgium	Science Advances	Cultural Heritage	O-PTIR	2022
Micro to nano: Multiscale IR analyses reveal zinc soap heterogeneity in a 19th-century painting by Corot https://doi.org/10.1021/acs.analchem.1c04182	Ma, X. et al Nanoscale Device Characterization Division, Physical Measurement Laboratory, NIST, USA	Analytical Chemistry	Cultural Heritage	O-PTIR	2022
Fibrosis mechanism, crystallization behavior and mechanical properties of in-situ fibrillary PTFE reinforced PP composites https://doi.org/10.1016/j.matdes.2021.110157	Zhang, A. et al Key Laboratory for Liquid-Solid Structural Evolution and Processing of Materials (Ministry of Education), Shandong University, Jinan, Shandong, China	Materials & Design	Polymers	O-PTIR	2021
Intrinsically disordered peptides enhance regenerative capacities of bone composite xenografts https://doi.org/10.1016/j.mattod.2021.12.001	Rahmati, M. et al Department of Biomaterials, Institute for Clinical Dentistry, University of Oslo, Norway	Materials Today	Life Sciences Bone regeneration Proteins Biomineralization	O-PTIR IR+Raman	2021
Steam disinfection releases micro(nano)plastics from silicone-rubber baby teats as examined by optical photothermal infrared microspectroscopy https://doi.org/10.1038/s41565-021-00998-x	Yu Su, et al. State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing University, Nanjing, China	Nature Nanotechnology	Environmental Microplastics	O-PTIR	2021
Comparing infrared spectroscopic methods for the characterization of Plasmodium falciparum-infected human erythrocytes https://doi.org/10.1038/s42004-021-00567-2	Banas, A., et al. Singapore Synchrotron Light Source, National University of Singapore	Nature, Communications Chemistry	Biomedical Red Blood Cells Malaria	O-PTIR	2021
Optical photothermal infrared microspectroscopy discriminates for the first time different types of lung cells on histopathology glass slides https://pubs.acs.org/doi/10.1021/acs.analchem.1c00309	Kansiz, M. et al. Photothermal Spectroscopy Corp	Analytical Chemistry	Life Science Cell differentiation	O-PTIR	2021
Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons https://doi.org/10.1038/s41377-021-00590-x	Gustavsson, N. et al. Medical Microspectroscopy, Department of Experimental Medical Science, Lund University, Sweden	Light: Science & Applications	Biomedical Neurons	O-PTIR	2021
Nanoscale analysis of historical paintings by means of O-PTIR spectroscopy: The identification of the organic particles in L’Arlésienne (portrait of Madame Ginoux) by Van Gogh https://doi.org/10.1002/anie.202106058	Beltran, V. et al AXES research group, University of Antwerp, Belgium	Angewandte Chemie	Cultural Heritage	O-PTIR	2021
Multiple antibiotics distribution in drinking water and their co-absorption behaviors by different size fractions of natural particles https://doi.org/10.1016/j.scitotenv.2021.145846	Zhao, P. et al Department of Environmental Engineering, School of Environmental Science and Engineering, Tianjin University, China	Science of The Total Environment	Environmental Microplastics	O-PTIR	2021
Analysis of fixed and live single cells using optical photothermal infrared with concomitant Raman spectroscopy https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04846	Spadea, A. et al University of Manchester, UK	Analytical Chemistry	Biomedical Fixed and live cells	O-PTIR IR+Raman OPO Transmission mode	2021
Imaging isotopically labeled bacteria at the single-cell level using high-resolution optical infrared photothermal spectroscopy https://pubs.acs.org/doi/10.1021/acs.analchem.0c03967	Lima C. et al Institute of Systems, Molecular and Integrative Biology, University of Liverpool, UK	Analytical Chemistry	Biomedical Bacteria	O-PTIR	2021
Resolving nanocomposite interfaces via simultaneous submicrometer optical-photothermal infrared-raman microspectroscopy https://onlinelibrary.wiley.com/doi/abs/10.1002/admi.202001720	Alexander J. Wang et al Advanced Manufacturing Institute, University of Houston	Advanced Material Interfaces	Materials science Nanocomposites	O-PTIR IR+Raman	2021
Optical photothermal infrared microspectroscopy with simultaneous Raman – a new non-contact failure analysis technique for identification of <10 μm organic contamination in the hard drive and other electronics industries https://doi.org/10.1017/S1551929520000917	Kansiz, M. et al Photothermal Spectroscopy Corp and Seagate Technology	Microscopy Today	Contamination Failure analysis	O-PTIR IR+Raman	2020
Super-resolution infrared imaging of polymorphic amyloid aggregates directly in neurons https://doi.org/10.1002/advs.201903004	Klementieva, O. et al Lund University	Advanced Science	Biomedical Neurons Fixed	O-PTIR	2020
Sub-micron, non-contact, super-resolution infrared microspectroscopy for microelectronics contamination and failure analyses https://ieeexplore.ieee.org/document/9261071	Lo, M. et. al. Photothermal Spectroscopy Corp.	2020 IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA)	Contamination Failure analysis	O-PTIR	2020
Orientation matters: Polarization dependent IR spectroscopy of collagen from intact tendon down to the single fibril Level https://www.mdpi.com/1420-3049/25/18/4295	Gough, K. M. et al Department of Chemistry, University of Manitoba, Canada	Molecules	Biomedical Collagen	O-PTIR Polarized IR	2020
Microplastic pollution in deep-sea sediments from the Great Australian Bight https://www.frontiersin.org/articles/10.3389/fmars.2020.576170	Barret J. et al. CSIRO, Oceans and Atmosphere, Hobart, TAS, Australia	Frontiers in Marine Research	Environmental Microplastics	O-PTIR	2020
Detection of high explosive materials within fingerprints by means of optical-photothermal infrared spectromicroscopy https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c00938	Banas, A. et al Singapore Synchrotron Light Source, National University of Singapore	Analytical Chemistry	Forensics Explosives	O-PTIR	2020
Simultaneous optical photothermal infrared (O-PTIR) and Raman spectroscopy of submicrometer atmospheric particles https://pubs.acs.org/doi/10.1021/acs.analchem.0c01495	Olson, N. et al University of Michigan	Analytical Chemistry	Microparticles Aerosols	O-PTIR IR+Raman	2020
Two-dimensional correlation analysis of highly spatially resolved simultaneous IR and Raman spectral imaging of bioplastics composite using optical photothermal infrared and Raman spectroscopy https://doi.org/10.1016/j.molstruc.2020.128045	Marcott, C. et al University of Delaware	The Journal of Molecular Structure	Polymers Laminates 2DCOS	O-PTIR IR+Raman	2020
Super resolution correlative far-field submicron simultaneous IR and raman microscopy: a new paradigm in vibrational spectroscopy https://doi.org/10.1117/12.2565489	Kansiz, M. et al Photothermal Spectroscopy Corp	Advanced Chemical Microscopy for Life Science and Translational Medicine	Analytical technique	O-PTIR IR+Raman	2020
Spontaneous formation of 2D-3D heterostructures on the edges of 2D Ruddlesden-Popper hybrid perovskite crystals https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.0c00419	Qin, Z. et al Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, and University of Houston	Chemistry of Materials	Materials science Perovskites	O-PTIR	2020
Bulk to nanometre-scale infrared spectroscopy of pharmaceutical dry powder aerosols https://doi.org/10.1021/acs.analchem.0c00729	Khanal, D. et al The University of Sydney	Analytical Chemistry	Pharmaceuticals Aerosols	O-PTIR	2020
Submicron-resolution polymer orientation mapping by optical photothermal infrared spectroscopy https://doi.org/10.1080/1023666X.2020.1735851	Baden, N. et al Nihon Thermal Consulting	International Journal of Polymer Analysis and Characterization	Polymers, polarization	O-PTIR	2020
Self-formed 2D/3D heterostructure on the edge of 2D ruddlesden-popper hybrid perovskites responsible for intriguing optoelectronic properties and higher cell efficiency https://arxiv.org/ftp/arxiv/papers/2001/2001.09477.pdf	Qin, Z. et al Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China	Physics, arXiv: Materials Science	Materials science - perovskites	O-PTIR	2020
Evolution of a radical-triggered polymerizing high internal phase emulsion into an open-cellular monolith https://doi.org/10.1002/macp.201900216	Li, C. et al Deartment of Polymer Materials, School of Materials Science and Engineering Tongji University	Macromolecular Chemistry and Physics	Polymers	O-PTIR	2019
Advances in infrared microspectroscopy and mapping molecular chemical composition at submicrometer spatial resolution Spectroscopy: Volume 33, Issue 9, pg 12–17	Reffner, J. et al John Jay College of Criminal Justice in New York	Spectroscopy	Polymers Fibers Forensics	O-PTIR	2018

Optical photothermal infrared microspectroscopy discriminates for the first time different types of lung cells on histopathology glass slides
https://pubs.acs.org/doi/10.1021/acs.analchem.1c00309

Author: Kansiz, M. et al.
Institution: Photothermal Spectroscopy Corp
Journal: Analytical Chemistry
Application: Life Science
Cell differentiation
Technique: O-PTIR
Year: 2021

Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
https://doi.org/10.1038/s41377-021-00590-x

Author: Gustavsson, N. et al.
Institution: Medical Microspectroscopy, Department of Experimental Medical Science, Lund University, Sweden
Journal: Light: Science & Applications
Application: Biomedical
Neurons
Technique: O-PTIR
Year: 2021

Nanoscale analysis of historical paintings by means of O-PTIR spectroscopy: The identification of the organic particles in L’Arlésienne (portrait of Madame Ginoux) by Van Gogh
https://doi.org/10.1002/anie.202106058

Author: Beltran, V. et al
Institution: AXES research group, University of Antwerp, Belgium
Journal: Angewandte Chemie
Application: Cultural Heritage
Technique: O-PTIR
Year: 2021

Multiple antibiotics distribution in drinking water and their co-absorption behaviors by different size fractions of natural particles
https://doi.org/10.1016/j.scitotenv.2021.145846

Author: Zhao, P. et al
Institution: Tianjin University, China
Journal: Science of The Total Environment
Application: environmental, microplastics
Technique: O-PTIR
Year: 2021

Analysis of fixed and live single cells using optical photothermal infrared with concomitant Raman spectroscopy
https://pubs.acs.org/doi/abs/10.1021/acs.analchem.0c04846

Author: Spadea, A. et al
Institution: University of Manchester, UK
Journal: Analytical Chemistry
Application: biomedical, fixed and live cells
Technique: O-PTIR, IR+Raman, OPO, Transmission mode
Year: 2021

Imaging isotopically labeled bacteria at the single-cell level using high-resolution optical infrared photothermal spectroscopy
https://pubs.acs.org/doi/10.1021/acs.analchem.0c03967

Author: Lima C. et al
Organization: University of Liverpool, UK
Journal: Analytical Chemistry
Application: biomedical, bacteria
Technique: O-PTIR
Year: 2021

Resolving nanocomposite interfaces via simultaneous submicrometer optical-photothermal infrared-raman microspectroscopy
https://onlinelibrary.wiley.com/doi/abs/10.1002/admi.202001720

Author: Alexander J. Wang et al
Institution: University of Houston
Journal: Advanced Material Interfaces
Application: materials science, nanocomposites
Technique: O-PTIR, IR+Raman
Year: 2021

Sub-micron, non-contact, super-resolution infrared microspectroscopy for microelectronics contamination and failure analyses
https://ieeexplore.ieee.org/document/9261071

Author: Lo, M. et al
Institution: Photothermal Spectroscopy Corp.
Journal: 2020 IEEE International Symposium on the Physical and Failure Analysis of Integrated Circuits (IPFA)
Application: contamination, failure analysis
Technique: O-PTIR
Year: 2021

Orientation matters: Polarization dependent IR spectroscopy of collagen from intact tendon down to the single fibril Level
https://www.mdpi.com/1420-3049/25/18/4295

Author: Gough, K. M. et al
Institution:University of Manitoba, Canada
Journal: Molecules
Application: biomedical, collagen
Technique: O-PTIR, Polarized IR
Year: 2021

Microplastic pollution in deep-sea sediments from the Great Australian Bight
https://www.frontiersin.org/articles/10.3389/fmars.2020.576170

Author: Barret J. et al
Institution:(CSIRO) Oceans and Atmosphere, Australia
Journal: Frontiers in Marine Research
Application: environmental, microplastics
Technique: O-PTIR
Year: 2020

Detection of high explosive materials within fingerprints by means of optical-photothermal infrared spectromicroscopy
https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.0c00938

Author: Banas, A. et al
Institution:Singapore Synchrotron Light Source
Journal: Analytical Chemistry
Application: forensics, explosives
Technique: O-PTIR
Year: 2020

Simultaneous optical photothermal infrared (O-PTIR) and Raman spectroscopy of submicrometer atmospheric particles
https://pubs.acs.org/doi/10.1021/acs.analchem.0c01495

Author: Olson, N. et al
Institution: University of Michigan
Journal: Analytical Chemistry
Application: microparticles, aerosols
Technique: O-PTIR, IR+Raman
Year: 2020

Optical photothermal infrared microspectroscopy with simultaneous Raman ─ a new non-contact failure analysis technique for identification of <10 µm organic contamination in the hard drive and other electronics industries
https://doi.org/10.1017/S1551929520000917

Author
Author: Kansiz, M. et al
Institution: Photothermal Spectroscopy Corp and Seagate Technology
Journal: Microscopy Today
Application: contamination, failure analysis
Technique: O-PTIR, IR+Raman
Year: 2020

Two-dimensional correlation analysis of highly spatially resolved simultaneous IR and Raman spectral imaging of bioplastics composite using optical photothermal infrared and Raman spectroscopy
https://doi.org/10.1016/j.molstruc.2020.128045

Author: Marcott, C. et al
Institution:University of Delaware
Journal: The Journal of Molecular Structure
Application: polymers, laminates, 2DCOS
Technique: O-PTIR, IR+Raman
Year: 2020

Super resolution correlative far-field submicron simultaneous IR and Raman microscopy: a new paradigm in vibrational spectroscopy
https://doi.org/10.1117/12.2565489

Author: Kansiz, M. et al
Institution:Photothermal Spectroscopy Corp
Journal:Advanced Chemical Microscopy for Life Science and Translational Medicine
Application: analytical technique
Technique: O-PTIR, IR+Raman
Year: 2020

Super-resolution infrared imaging of polymorphic amyloid aggregates directly in neurons
https://doi.org/10.1002/advs.201903004

Author: Klementieva, O. et al
Institution: Lund University
Journal: Advanced Science
Application: biomedical, neurons fixed
Technique: O-PTIR
Year: 2020

Spontaneous formation of 2D-3D heterostructures on the edges of 2D Ruddlesden-Popper hybrid perovskite crystals
https://pubs.acs.org/doi/abs/10.1021/acs.chemmater.0c00419

Author: Qin, Z. et al
Institution: University of Electronic Science and Technology of China,
and University of Houston
Journal: Chemistry of Materials
Application: materials science, perovskites
Technique: O-PTIR
Year: 2020

Bulk to nanometre-scale infrared spectroscopy of pharmaceutical dry powder aerosols
https://doi.org/10.1021/acs.analchem.0c00729

Author
Author: Khanal, D. et al
Institution: The University of Sydney
Journal: Analytical Chemistry
Application: pharmaceuticals, aerosols
Technique: O-PTIR
Year: 2020

A global perspective on microplastics
https://doi.org/10.1029/2018JC014719

Author: Hale, R. et al
Institution: Virginia Institute of Marine Science
Journal: Journal of Geophysical Research: Ocean
Application: environment microplastics
Technique: O-PTIR, IR+Raman
Year: 2020

Submicron-resolution polymer orientation mapping by optical photothermal infrared spectroscopy
https://doi.org/10.1080/1023666X.2020.1735851

Author: Baden, N. et al
Institution: Nihon Thermal Consulting
Journal: International Journal of Polymer Analysis and Characterization
Application: polymers, polarization
Technique: O-PTIR
Year: 2020

Self-formed 2D/3D heterostructure on the edge of 2D ruddlesden-popper hybrid perovskites responsible for intriguing optoelectronic properties and higher cell efficiency
https://arxiv.org/ftp/arxiv/papers/2001/2001.09477.pdf

Author: Qin, Z. et al
Institution: University of Electronic Science and Technology of China
Journal: Physics, arXiv: Materials Science
Application: materials science – perovskites
Technique: O-PTIR
Year: 2020

Evolution of a radical-triggered polymerizing high internal phase emulsion into an open-cellular monolith
https://doi.org/10.1002/macp.201900216

Author: Li, C. et al
Institution:School of Materials Science and Engineering Tongji University
Journal: Macromolecular Chemistry and Physics
Application: polymers
Technique: O-PTIR
Year: 2019

Advances in infrared microspectroscopy and mapping molecular chemical composition at submicrometer spatial resolution
Spectroscopy: Volume 33, Issue 9, pg 12-17

Author: Reffner, J. et al
Institution: John Jay College of Criminal Justice in New York
Journal: Spectroscopy
Application: Polymers, Fibers, Forensics
Technique: O-PTIR
Year: 2018