Curt Marcott, Photothermal Spectroscopy Corp scientific partner wins 2023 NY/NJ Society of Applied Spectroscopy Gold Medal Award

Curt Marcott, Photothermal Spectroscopy Corp scientific partner wins 2023 NY/NJ Society of Applied Spectroscopy Gold Medal Award

Dr. Marcott of Light Light Solutions

Santa Barbara, California – Photothermal Spectroscopy Corp announces that its Scientific Partner, Dr Curtis Marcott has won the NY/NJ Section of the Society for Applied Spectroscopy Gold Medal Award. This coveted award was established in 1952 to recognize outstanding contributions to the field of Applied Spectroscopy.
Dr. Marcott of Light Light Solutions has played a significant role in the commercialization of sub-diffraction IR spectroscopy using photothermal infrared (PTIR), including AFM-PTIR, optical PTIR (O-PTIR), and the simultaneous measurement of O-PTIR and Raman spectra. Curt previously was employed by the Procter & Gamble Company where he worked for over 28 years in the Optical Spectroscopy Laboratory and was named Research Fellow in 1997.
The O-PTIR approach achieves significant performance benefits over conventional IR spectroscopy including >10X better spatial resolution, operation in both transmission and reflection modes without scattering artifacts, and operation in a non-contact mode. This technology is now used internationally at many top university and government research laboratories and industrial facilities, including several Fortune 500 companies.

Curt will be honored at the 2023 Eastern Analytical symposium in Plainsboro, NJ, November Tuesday afternoon in a special awards session, Tuesday Nov 14th
The 2023 Award Symposium will feature an award address by Curt and talks from his invited speakers.

The invited speakers are:

Isao Noda,
University of Delaware: Industrial Spectroscopy Research Leading to the Development of Novel Bioplastics.

Craig Prater,
Photothermal Spectroscopy Corp: Super-Resolution Photothermal Infrared Spectroscopy for Science and Industry.

Simone Ruggeri,
Wageningen University: Multimodal Infrared Nanospectroscopy in the Bio- and Materials Sciences.

Curtis Marcott,
Light Light Solutions: Chemically Characterizing the Microstructure of Novel Bioplastics Using Photothermal Infrared Spectroscopy.

About Curt Marcott

Dr. Curtis Marcott is a Senior Partner at Light Light Solutions LLC, a spectroscopic consulting firm. He received a B.S. in math and chemistry at Concordia College and his PhD from University of Minnesota. Following his PhD, he joined The Procter & Gamble Company where he worked for over 28 years in the Optical Spectroscopy Laboratory and was named Research Fellow in 1997. Dr. Curtis Marcott joined Light Light Solutions LLC in 2008.
Dr. Marcott contributed to a number of innovative developments in vibrational spectroscopy: vibrational circular dichroism (VCD), near-IR measurements of interfacial phase boundaries, 2D correlation spectroscopy, publication of the first polarization modulation grazing angle FT-IR measurements of monolayers on metals and the first FT-IR spectroscopic imaging measurements using a focal plane array (FPA). At Light Light Solutions he played key roles in the commercialization of sub-diffraction IR spectroscopy using photothermal infrared (PTIR), including AFM-PTIR, optical PTIR (O-PTIR), and the simultaneous measurement of O-PTIR and Raman spectra.
Curt is well known in the field of vibrational spectroscopy for his intellectual and professional leadership. He has mentored and inspired many younger scientists to explore the potential of spectroscopy. His breadth of knowledge relating to vibrational spectroscopy interpretation is extensive and he intimately understands molecular vibrations from both the experimental measurement and theoretical perspectives.
Dr. Marcott has authored and co-authored more than 150 publications, given more than 650 presentations at national and international meetings. He is a past president of the Society for Applied Spectroscopy and has served on numerous conference organizing committees and journal editorial advisory boards. For his work Dr. Marcott received the 1993 Williams-Wright Award from the Coblentz Society for achievement in industrial vibrational spectroscopy and was named the 2001 Cincinnati Chemist of the Year.

Further Information can Be found here:
NY/NJ Section of the Society for Applied Spectroscopy Gold Medal Award: – Eastern Analytical Symposium

Details of the Award Symposium can be found here:
https://eas.org/wp-content/uploads/2023/08/EAS-2023-Updated-Preliminary-Program.pdf


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC), the sub-micron spectroscopy company, has pioneered the breakthrough technique of optical Photothermal Infrared (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy providing submicron spatial resolution for IR and transmission-like FTIR quality spectra in non-contact reflection mode. More recently, PSC has developed the world’s first simultaneous Infrared and Raman microscope and imaging system, providing IR and Raman data from the exact same spot, at the same time, with the same submicron spatial resolution. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


Media Contact: Dean Dawson, V.P. Marketing and Business Development Photothermal Spectroscopy Corp T: +1 (805) 845-6568 x525 www.photothermal.com

PSC opens new european office to support increased regional growth

PSC opens new european office to support increased regional growth

Dr. Miriam Unger, Director of European Applications, with the mIRage-R O-PTIR system with simultaneous Raman spectroscopy in the Photothermal Spectroscopy Corp. GmbH, Essen, Germany based office

Santa Barbara, California – Photothermal Spectroscopy Corp. announces new European Applications and Support Office to Support Strong Growth in sub-micron O-PTIR installations.

Photothermal Spectroscopy Corp. (PSC), a pioneer in the development of sub-micron IR spectroscopy via O-PTIR (Optical Photothermal IR) Spectroscopy, is excited to announce the opening of a new European office in Essen, Germany. This strategic expansion aims to better support the company’s rapidly growing customer base across Europe by offering localized applications, and service support.
Managed by Dr. Miriam Unger, Director of European Applications, the new office will serve as a hub for PSC’s European Applications and service support. Dr. Unger’s scientific leadership in photothermal IR spectroscopy promises to deliver a high level of expertise to the European market.

“Our new office in Essen allows us to be closer to our European customers and partners,” said Dr. Unger. “The facility is equipped with a state-of-the-art demonstration center featuring our cutting-edge mIRage-LS system, complete with Raman and fluorescence options, which allows prospective clients to experience our technology firsthand.”

Mr. Sergey Mitko recently joined us to ensure first-class support for the growing European customer installed base. The Essen office will serve as a pivotal location for timely, efficient, and personalized service solutions.

“Having a dedicated European office improves our ability to offer responsive and localized service,” said Mr. Mitko. “We understand the importance of maintaining customer productivity and enhancing user experience, and our Essen base will play a crucial role in achieving these goals.”

Dean Dawson, VP of Marketing adds “We are excited to open our applications and support center in Germany to provide both an increased level of support for our existing European customers and to support our future customer growth. We will continue to work with our existing channel partner network in the region to provide the highest level of applications and technical support”.

For more information about the new European office or to schedule a product demonstration, please contact Dr. Miriam Unger at [email protected].

Photothermal Spectroscopy Corp. GmbH
Demonstration and support Office
Sittardsberger Allee 154, 47249
Duisburg, Germany


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC), the sub-micron spectroscopy company, has pioneered the breakthrough technique of optical Photothermal Infrared (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy providing submicron spatial resolution for IR and transmission-like FTIR quality spectra in non-contact reflection mode. More recently, PSC has developed the mirage-LS. The world’s first sub-micron Infrared and co-located fluorescence microscope. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


About mIRage®-LS

The mIRage-LS IR multimodal microscope integrates the combined technologies of Raman and Fluorescence microscopy with sub-micron IR spatial resolution imaging and spectroscopy using Optical Photothermal IR (O-PTIR) spectroscopy. These combined techniques will enable life science researchers to easily identify bio-molecular structures of interest and characterize their chemical structure with submicron IR.

Fluorescence microscopy, with its powerful molecular specificity has been a life science research workhorse technique for decades. Vibrational spectroscopy (IR & Raman) are well established techniques, providing broad macromolecular, spatially resolved characterization abilities for life science-based applications.

With the recent advent of O-PTIR, with its submicron and simultaneous Raman capabilities, this broad macromolecular characterization can now be performed on biologically relevant spatial scales, <500 nm, allowing uniquely for IR spectroscopy, sub-cellular resolution, which is matched with Raman and fluorescence imaging resolution.

Now, for the first time, a fully integrated and sample registration free combination of these techniques into a single platform heralds a breakthrough for life science research, allowing researchers to truly exploit these two techniques with powerful synergy, to access additional information and insights not available with either technique on its own.


Media Contact: Dean Dawson, V.P. Marketing and Business Development Photothermal Spectroscopy Corp T: +1 (805) 845-6568 x525 www.photothermal.com

New fluorescence guided OPTIR highlights new advancements in neuroscience

New fluorescence guided OPTIR highlights new advancements in neuroscience

J. Med. Chem. 2023, 66, 4, 2542–2549

Santa Barbara, California – Photothermal Spectroscopy Corp. announces the first scientific publication highlight advances in neuroscience with its new technology of Fluorescence guided Optical Photothermal Infrared (FL-OPTIR) spectroscopy on the mIRage®-LS platform. The publication was highlighted on the front cover of the Journal of Medicinal Chemistry, a journal of ACS publications in the February 23, 2023 issue.

The publication titled “Fluorescently guided optical photothermal infrared microspectroscopy for protein-specific bioimaging at subcellular level” authored by Dr. Oxana Klementieva, Associate Professor, Molecular Imaging, Lund University, Sweden and her colleagues in combination with Dr. Craig Prater CTO, Photothermal Spectroscopy Corp and Dr. Yeran Bai, post-doctoral researcher, University California, Santa Barbara.

The publication demonstrated significant methodological advances that allow for the studies of vulnerable parts of neurons being attacked by amyloids. This will lead to a better understanding of amyloid protein aggregation in complex systems such as tissues as well as living cell studies.

“I am very excited about new possibilities that can now be achieved with fluorescence guided OPTIR on the mIRage®-LS for biomedical research. The new instrument offers a dream setup for microspectroscopic experiments.” stated Dr. Klementieva, “I strongly believe that fluorescence guided OPTIR on the mIRage®-LS can be useful for many research groups addressing protein misfolding involved in Alzheimer’s, Parkinson’s, brain trauma, and COVID related lung structural changes of collagen and many more applications”.
Dr. Craig Prater commented “Fluorescence-guided photothermal infrared spectroscopy on the mIRage®-LS platform allows researchers to fluorescently label targeted molecules in cells and tissue and then perform infrared spectroscopic analysis on both labeled and unlabeled regions of the sample. In our recent publication, we used fluorescent labels to tag amyloids in brain tissue and then used FL-OPTIR to measure difference in beta sheet formation between normal and diseased tissue. The FL-OPTIR approach can be used to chemically analyze specifically targeted molecular structures in complex samples such as biological tissue at the subcellular level.”

The link to the publication can be found here:
Fluorescently guided optical photothermal infrared microspectroscopy for protein-specific bioimaging at subcellular level, “Journal of Medicinal Chemistry” (acs.org)

J. Med. Chem. 2023, 66, 4, 2542–2549
Publication Date: January 4, 2023
https://doi.org/10.1021/acs.jmedchem.2c01359
Copyright © 2023 The Authors. Published by American Chemical Society

Further information about Dr Oxana Klementieva can be found here:
Oxana Klementieva — Lund University


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC), the sub-micron spectroscopy company, has pioneered the breakthrough technique of optical Photothermal Infrared (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy providing submicron spatial resolution for IR and transmission-like FTIR quality spectra in non-contact reflection mode. More recently, PSC has developed the world’s first simultaneous Infrared and Raman microscope and imaging system, providing IR and Raman data from the exact same spot, at the same time, with the same submicron spatial resolution. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


About mIRage®-LS

The mIRage-LS IR multimodal microscope integrates the combined technologies of Raman and Fluorescence microscopy with sub-micron IR spatial resolution imaging and spectroscopy using Optical Photothermal IR (O-PTIR) spectroscopy. These combined techniques will enable life science researchers to easily identify bio-molecular structures of interest and characterize their chemical structure with submicron IR.

Fluorescence microscopy, with its powerful molecular specificity has been a life science research workhorse technique for decades. Vibrational spectroscopy (IR & Raman) are well established techniques, providing broad macromolecular, spatially resolved characterization abilities for life science-based applications.

With the recent advent of O-PTIR, with its submicron and simultaneous Raman capabilities, this broad macromolecular characterization can now be performed on biologically relevant spatial scales, <500 nm, allowing uniquely for IR spectroscopy, sub-cellular resolution, which is matched with Raman and fluorescence imaging resolution.

Now, for the first time, a fully integrated and sample registration free combination of these techniques into a single platform heralds a breakthrough for life science research, allowing researchers to truly exploit these two techniques with powerful synergy, to access additional information and insights not available with either technique on its own.


Media Contact: Dean Dawson, V.P. Marketing and Business Development Photothermal Spectroscopy Corp T: +1 (805) 845-6568 x525 www.photothermal.com

NEW mIRage-LS sub-500nm IR spectroscopy system with simultaneous Raman and co-located Fluorescence microscopy

Santa Barbara, California – Photothermal Spectroscopy Corp announces the new mIRage®-LS sub-500nm IR multimodal microscope and spectroscopy system uniquely combining, simultaneous Raman and co-located Fluorescence Microscopy with sub-micron IR in a single platform. Additionally, new developments on their proprietary O-PTIR (Optical photothermal IR Spectroscopy) technique have pushed the IR spatial resolution to sub 500nm and beyond for life science related applications.

This new integrated platform uniquely combines the benefits of fluorescence microscopy to support fast, easy targeting of molecular features of interest with sub-micron IR spectroscopy to characterize the molecular structure of bio-molecular features, including sub-cellular and tissue applications.

“I am very excited about the potential of the mirage LS, combining (O-PTIR) with co-located Fluorescence microscopy for the same sample region. It combines the exquisite sensitivity of fluorescence microscopy with the powerful molecular structural capabilities of infrared spectroscopy at a sub 500nm spatial resolution” stated Professor Kenneth Kosik, USCB Harriman Professor of Neuroscience and co-director of the Neuroscience research institute.
“This combination of sub 500nm IR with collocated fluorescence will enable us to obtain valuable insight towards several high value questions concerning protein folding and aggregation that interest my group”.

“The new mIRage-LS builds on our O-PTIR measurement technique providing wavelength independent, true sub-micron spatial resolution for both spectroscopy and imaging and combined sub-micron Raman and IR spectroscopy.” stated Dr Mustafa Kansiz, Director of Product Management, Photothermal Spectroscopy Corp.

“The mirage LS also provide significant improvements in IR spatial resolution enabling us to target ever smaller bio-molecular features providing a breakthrough in IR characterization for a wide range of life science applications.”

Further information relating to the mIRage-LS can be found here:
Co-located fluorescence OPTIR – Optical photothermal infrared and Raman spectroscopy with the mIRage


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC), the sub-micron spectroscopy company, has pioneered the breakthrough technique of optical Photothermal Infrared (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy providing submicron spatial resolution for IR and transmission-like FTIR quality spectra in non-contact reflection mode. More recently, PSC has developed the world’s first simultaneous Infrared and Raman microscope and imaging system, providing IR and Raman data from the exact same spot, at the same time, with the same submicron spatial resolution. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


About mIRage®-LS

The mIRage-LS IR multimodal microscope integrates the combined technologies of Raman and Fluorescence microscopy with sub-micron IR spatial resolution imaging and spectroscopy using Optical Photothermal IR (O-PTIR) spectroscopy. These combined techniques will enable life science researchers to easily identify bio-molecular structures of interest and characterize their chemical structure with submicron IR.

Fluorescence microscopy, with its powerful molecular specificity has been a life science research workhorse technique for decades. Vibrational spectroscopy (IR & Raman) are well established techniques, providing broad macromolecular, spatially resolved characterization abilities for life science-based applications.

With the recent advent of O-PTIR, with its submicron and simultaneous Raman capabilities, this broad macromolecular characterization can now be performed on biologically relevant spatial scales, <500nm, allowing uniquely for IR spectroscopy, sub-cellular resolution, which is matched with Raman and fluorescence imaging resolution.

Now, for the first time, a fully integrated and sample registration free combination of these techniques into a single platform heralds a breakthrough for life science research, allowing researchers to truly exploit these two techniques with powerful synergy, to access additional information and insights not available with either technique on its own.


Media Contact: Molly Morrison, Marketing Manager Photothermal Spectroscopy Corp T: +1 (805) 845-6568 x525 www.photothermal.com

O-PTIR co-inventor wins 2019 Lippincott Award

Santa Barbara, Calif. – November 5, 2019 – The 2019 Ellis R. Lippincott Award was presented to co-inventor of the Optical Photothermal IR (O-PTIR) technique that is the basis for the operation of the mIRage IR microscope. The award is given for “outstanding contributions in inventing and developing a broad spectrum of vibrational spectroscopic imaging technologies with groundbreaking discoveries and clinical applications.” Presentation of the 2019 award was at SciX 2019 in Palm Springs, California.

Ji-Xin Cheng attended the University of Science and Technology of China from 1989 to 1994 and pursued a PhD study on bond-selective chemistry from 1994 to 1998. In 2000 he joined the Sunney Xie’s group at Harvard University as a postdoc. Cheng subsequently joined Purdue University in 2003 as Assistant Professor and was promoted to Associate Professor in 2009 and Full Professor in 2013. He joined Boston University as the Inaugural Moustakas Chair Professor in Photonics and Optoelectronics in 2017.

Ji-Xin Cheng has devoted his career to transforming molecular spectroscopy from an in vitro analytical tool to a set of in vivo label-free chemical imaging platforms for the discovery of hidden signatures inside living systems and further translation of the discoveries into medical diagnosis and treatment strategies.


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC) is a spin-off from Anasys Instruments Corp, the company that pioneered the field of AFM-based photothermal IR spectroscopy (PTIR) and was eventually acquired by Bruker Nano. PSC now has a breakthrough optical PTIR (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy: spatial resolution and sample preparation. O-PTIR provides sub-micron spatial resolution for IR and provides transmission-like FTIR quality spectra in non-contact reflection mode. O-PTIR provides all the benefits of ATR without contact-related limitations, and also provides Raman-like spatial resolution, but with IR sensitivity. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


About mIRage®

The mIRage IR microscope provides true sub-micron IR spatial resolution imaging and spectroscopy using Optical Photothermal IR (O-PTIR) spectroscopy, a proprietary technique. mIRage provides wavelength independent spatial resolution, highly sensitive IR measurements and transmission quality absorption spectra in refection mode. mIRage bridges the gap between conventional IR microspectroscopy and AFM-based nanoscale IR spectroscopy.


Media Contact: Molly Morrison, Marketing Manager Photothermal Spectroscopy Corp T: +1 (805) 845-6568 x525 www.photothermal.com

Photothermal Spectroscopy Corp announced winner of R&D 100 Awards

Santa Barbara, Calif. – December 1, 2018 – Photothermal Spectroscopy Corp, the pioneer in Optical Photothermal IR (O-PTIR) spectroscopy, has been announced a winner of the 2018 R&D 100 Awards.

Photothermal Spectroscopy Corp’s product, the mIRage IR Microscope, was developed in mid-2017 and launched at the SciX Conference in Reno, NV in October 2017. The system is the first of its kind, utilizing Photothermal Spectroscopy Corp’s proprietary technology, Optical Photothermal IR (O-PTIR) spectroscopy.

“We are humbled to receive this recognition from R&D Magazine,” stated Roshan Shetty, CEO. “Our staff and collaborators have developed a truly groundbreaking technology and system. Submicron IR spectroscopy in a non-contact reflection mode technique will aid many researchers in breaking barriers in IR analysis. We are excited to see even more applications capabilities opening up next year.”

Since its initial development, and in a world first, Photothermal Spectroscopy Corp has developed and launched IR&Raman – simultaneous submicron IR and Raman microscopy on the mIRage IR Microscope platform, providing simultaneous IR and Raman data from the same submicron spot at the same time and with the same spatial resolution


About Photothermal Spectroscopy Corp

Photothermal Spectroscopy Corp (PSC) is a spin-off from Anasys Instruments Corp, the company that pioneered the field of AFM-based photothermal IR spectroscopy (PTIR) and was eventually acquired by Bruker Nano. PSC now has a breakthrough optical PTIR (O-PTIR) technology that eliminates key limitations of traditional IR Spectroscopy: spatial resolution and sample preparation. O-PTIR provides sub-micron spatial resolution for IR and provides transmission-like FTIR quality spectra in non-contact reflection mode. O-PTIR provides all the benefits of ATR without contact-related limitations, and also provides Raman-like spatial resolution, but with IR sensitivity. PSC’s vision is to enable the power of IR spectroscopy to be applied to high value problems in industry and academia via the adoption of O-PTIR.


About mIRage®

The mIRage IR microscope provides true sub-micron IR spatial resolution imaging and spectroscopy using Optical Photothermal IR (O-PTIR) spectroscopy, a proprietary technique. mIRage provides wavelength independent spatial resolution, highly sensitive IR measurements and transmission quality absorption spectra in refection mode. mIRage bridges the gap between conventional IR microspectroscopy and AFM-based nanoscale IR spectroscopy.